Seven mobile oxazolidinone resistance genes, including cfr, cfr (B), cfr (C), cfr (D), cfr (E),
optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases …

Vancomycin-resistant enterococci (VRE) are both of medical and public health importance
associated with serious multidrug-resistant infections and persistent colonization …

The oxazolidinones (linezolid and tedizolid) are last-resort antimicrobial agents used for the
treatment of severe infections in humans caused by MDR Gram-positive bacteria. They bind …

Enterococcus species are natural inhabitants of the intestinal tract in humans and animals,
and due to their ubiquity in human and animal feces and their persistence in the …

Vancomycin-resistant enterococci (VRE) are important nosocomial pathogens. Invasive VRE
infections are difficult to treat since common therapeutic options including ampicillin and …

Antimicrobial agents are used in both veterinary and human medicine. The intensive use of
antimicrobials in animals may promote the fixation of antimicrobial resistance genes in …

Enterococci are commensals of the intestinal tract of many animals and humans. Of the
various known and still unnamed new enterococcal species, only isolates of Enterococcus …

Linezolid is considered a last resort drug in treatment of severe infections caused by Gram-
positive pathogens, resistant to other antibiotics, such as vancomycin-resistant enterococci …

Objectives This study evaluated the oxazolidinone resistance mechanisms among a global
collection of enterococcal clinical isolates. The epidemiology of optrA-carrying isolates and …

Enterococcus are opportunistic pathogens that have been gaining importance in the clinical
setting, especially in terms of hospital-acquired infections. This problem has mainly been …