Arterial spin labeling (ASL) magnetic resonance imaging uses arterial blood water as an
endogenous tracer to measure cerebral blood flow (CBF). In this review, based on ASL …

Visualization of cerebral blood flow (CBF) has become an important part of neuroimaging for
a wide range of diseases. Arterial spin labeling (ASL) perfusion magnetic resonance …

Objective To characterize in vivo signatures of pathological diagnosis in a large cohort of
patients with primary progressive aphasia (PPA) variants defined by current diagnostic …

Objective: To describe the phenotype of patients with C9FTD/ALS (C9ORF72)
hexanucleotide repeat expansion. Methods: A total of 648 patients with frontotemporal …

Importance We provide novel evidence of specific clinical and neuroimaging features that
may help for the in vivo prediction of underlying pathology in patients with …

Developing and validating sensitive biomarkers for the presymptomatic stage of familial
frontotemporal dementia is an important step in early diagnosis and for the design of future …

Primary progressive aphasia is a neurodegenerative clinical syndrome that presents in
adulthood with an isolated, progressive language disorder. Three main clinical/anatomical …

Neurodegenerative disorders leading to dementia are common diseases that affect many
older and some young adults. Neuroimaging methods are important tools for assessing and …

Importance The ability to predict the pathology underlying different neurodegenerative
syndromes is of critical importance owing to the advent of molecule-specific therapies …

Despite considerable interest in improving clinical and neurobiological characterisation of
frontotemporal dementia and in defining the role of brain network disintegration in its …