Digital health for optimal supportive care in oncology: benefits, limits, and future perspectives
Background Digital health provides solutions that capture patient-reported outcomes (PROs)
and allows symptom monitoring and patient management. Digital therapeutics is the …
and allows symptom monitoring and patient management. Digital therapeutics is the …
Molecular and cellular functions of CTLA-4
S Van Coillie, B Wiernicki, J Xu - Regulation of Cancer Immune …, 2020 - Springer
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is an inhibitory receptor belonging to
the CD28 immunoglobulin subfamily, expressed primarily by T-cells. Its ligands, CD80 and …
the CD28 immunoglobulin subfamily, expressed primarily by T-cells. Its ligands, CD80 and …
Lessons to be learnt from real-world studies on immune-related adverse events with checkpoint inhibitors: a clinical perspective from pharmacovigilance
E Raschi, M Gatti, F Gelsomino, A Ardizzoni… - Targeted Oncology, 2020 - Springer
The advent of immune checkpoint inhibitors (ICIs) caused a paradigm shift both in drug
development and clinical practice; however, by virtue of their mechanism of action, the …
development and clinical practice; however, by virtue of their mechanism of action, the …
Improved survival in patients with thyroid function test abnormalities secondary to immune-checkpoint inhibitors
J Lima Ferreira, C Costa, B Marques, S Castro… - Cancer Immunology …, 2021 - Springer
Immune-checkpoint inhibitors (ICI) are monoclonal antibodies which target molecules to
enhance antitumor response. Several adverse events have been described and the major …
enhance antitumor response. Several adverse events have been described and the major …
Immunomodulatory Precision: A Narrative Review Exploring the Critical Role of Immune Checkpoint Inhibitors in Cancer Treatment
J Qiu, Z Cheng, Z Jiang, L Gan, Z Zhang… - International Journal of …, 2024 - mdpi.com
An immune checkpoint is a signaling pathway that regulates the recognition of antigens by T-
cell receptors (TCRs) during an immune response. These checkpoints play a pivotal role in …
cell receptors (TCRs) during an immune response. These checkpoints play a pivotal role in …
Immunotherapy in adrenocortical carcinoma: predictors of response, efficacy, safety, and mechanisms of resistance
M Araujo-Castro, E Pascual-Corrales, J Molina-Cerrillo… - Biomedicines, 2021 - mdpi.com
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy with limited treatment
options in the advanced stages. Immunotherapy offers hope for altering the orthodox …
options in the advanced stages. Immunotherapy offers hope for altering the orthodox …
Adjuvant therapy for renal cell carcinoma: End points, outcomes, and risk assessments
JJ Boyle, JL Pfail, BJ Lichtbroun, EA Singer - JCO Precision Oncology, 2023 - ascopubs.org
PURPOSE Targeted tyrosine kinase inhibitors (TKIs) and immune-checkpoint inhibitors
(ICIs) revolutionized the treatment of metastatic renal cell carcinoma (RCC). Efforts to …
(ICIs) revolutionized the treatment of metastatic renal cell carcinoma (RCC). Efforts to …
Delving into the clinical impact of NETs in pediatric cancer
N Benavent, A Cañete, B Argilés, A Juan-Ribelles… - Pediatric …, 2024 - nature.com
Pediatric cancer, a complex and heterogeneous group of diseases, continues to challenge
medical research and treatment strategies. Despite advances in precision medicine and …
medical research and treatment strategies. Despite advances in precision medicine and …
Digital health for optimal supportive care in oncology: benefits, limits, and future perspectives
Background: Digital health provides solutions that capture pa-tient-reported outcomes
(PROs) and allows symptom monitoring and patient management. Digital therapeutics is the …
(PROs) and allows symptom monitoring and patient management. Digital therapeutics is the …
Immunotherapy in cancer management: a literature review of clinical efficacy of pembrolizumab in the non-small cell lung cancer treatment
LB Miquelotti, MHM Sari… - Advanced Pharmaceutical …, 2021 - pmc.ncbi.nlm.nih.gov
Purpose: Cancer is a global public health problem that affects millions of people every year
and the immunotherapy has been a promising alternative for its treatment. The aim of this …
and the immunotherapy has been a promising alternative for its treatment. The aim of this …