Immunotherapy has greatly improved outcomes for subgroups of patients with cancer. As
indications keep expanding, there is an unmet need to gain a better understanding of the …

Highlights•This review collected the available evidence on the role of immunotherapy on
fertility, hypogonadism, and sexuality.•Immune checkpoint inhibitors could impair fertility.• …

Cancer during pregnancy is relatively rare but is increasing in frequency in countries in
which the maternal child-bearing age continues to rise. The complexities of medical decision …

Successful pregnancy is a unique situation requires the maternal immune system to
recognize and tolerate a semi‐identical fetus and allow normal invasion of trophoblast cells …

Introduction Little is known about placental and fetal metastases among pregnant women
with cancer. Therefore, we conducted a systematic review to identify the clinical and …

Background Immune checkpoint inhibitors have been widely implemented in current clinical
practice. Although cancer occurs in∼ 1 out of 1000 pregnancies, treatment remains …

Background: Immune checkpoint immunotherapy (CPI) targeting programmed cell death 1
(PD-1)/ligand (PD-L1) has been shown to be an effective treatment for gestational …

The treatment of cancer during pregnancy presents a unique challenge. Optimal treatments
are often altered or even delayed to protect fetal growth and organogenesis. The landscape …

Despite a significant amount of data on incidence and therapy of immune-related adverse
events affecting virtually all organ systems, the potential impact of immune checkpoint …

Approximately one-third of women diagnosed with melanoma are of child-bearing age. The
annual incidence of melanoma has risen steadily over the last 40 years, resulting in …