Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and …
JC Frisvad, LLH Møller, TO Larsen, R Kumar… - Applied Microbiology …, 2018 - Springer
This review presents an update on the current knowledge of the secondary metabolite
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
potential of the major fungal species used in industrial biotechnology, ie, Aspergillus niger …
Taxonomy of Aspergillus section Flavi and their production of aflatoxins, ochratoxins and other mycotoxins
JC Frisvad, V Hubka, CN Ezekiel, SB Hong… - Studies in …, 2019 - ingentaconnect.com
Aflatoxins and ochratoxins are among the most important mycotoxins of all and producers of
both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same …
both types of mycotoxins are present in Aspergillus section Flavi, albeit never in the same …
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi
Genomics has revolutionized the research on fungal secondary metabolite (SM)
biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the …
biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the …
Biosynthesis of the halogenated mycotoxin aspirochlorine in koji mold involves a cryptic amino acid conversion
P Chankhamjon, D Boettger‐Schmidt… - Angewandte …, 2014 - Wiley Online Library
Abstract Aspirochlorine (1) is an epidithiodiketopiperazine (ETP) toxin produced from koji
mold (Aspergillus oryzae), which has been used in the oriental cuisine for over two …
mold (Aspergillus oryzae), which has been used in the oriental cuisine for over two …
Sensitive deep-sequencing-based HIV-1 genotyping assay to simultaneously determine susceptibility to protease, reverse transcriptase, integrase, and maturation …
With 29 individual antiretroviral drugs available from six classes that are approved for the
treatment of HIV-1 infection, a combination of different phenotypic and genotypic tests is …
treatment of HIV-1 infection, a combination of different phenotypic and genotypic tests is …
Motif-Independent Prediction of a Secondary Metabolism Gene Cluster Using Comparative Genomics: Application to Sequenced Genomes of Aspergillus and Ten …
Despite their biological importance, a significant number of genes for secondary metabolite
biosynthesis (SMB) remain undetected due largely to the fact that they are highly diverse …
biosynthesis (SMB) remain undetected due largely to the fact that they are highly diverse …
Whole genome sequencing of the black grouse (Tetrao tetrix): reference guided assembly suggests faster-Z and MHC evolution
Background The different regions of a genome do not evolve at the same rate. For example,
comparative genomic studies have suggested that the sex chromosomes and the regions …
comparative genomic studies have suggested that the sex chromosomes and the regions …
Harnessing cross-species alignment to discover SNPs and generate a draft genome sequence of a bighorn sheep (Ovis canadensis)
Background Whole genome sequences (WGS) have proliferated as sequencing technology
continues to improve and costs decline. While many WGS of model or domestic organisms …
continues to improve and costs decline. While many WGS of model or domestic organisms …
Diagnosis and management of invasive fungal diseases by next-generation sequencing: are we there yet?
NE Babady, CY Chiu, A Craney… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Invasive fungal diseases (IFDs) are a serious threat to
immunocompromised patients. Routine diagnostic methods have limited performance in …
immunocompromised patients. Routine diagnostic methods have limited performance in …
Motif-independent de novo detection of secondary metabolite gene clusters—toward identification from filamentous fungi
Secondary metabolites are produced mostly by clustered genes that are essential to their
biosynthesis. The transcriptional expression of these genes is often cooperatively regulated …
biosynthesis. The transcriptional expression of these genes is often cooperatively regulated …