New advances in general biomedical applications of PAMAM dendrimers

RV Araújo, SS Santos, E Igne Ferreira, J Giarolla - Molecules, 2018 - mdpi.com
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …

Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics …

D Astruc, E Boisselier, C Ornelas - Chemical reviews, 2010 - ACS Publications
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular
Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and …

Graphene quantum dots prevent α-synucleinopathy in Parkinson's disease

D Kim, JM Yoo, H Hwang, J Lee, SH Lee… - Nature …, 2018 - nature.com
Though emerging evidence indicates that the pathogenesis of Parkinson's disease is
strongly correlated to the accumulation, and transmission, of α-synuclein (α-syn) aggregates …

Nanoparticles in relation to peptide and protein aggregation

M Zaman, E Ahmad, A Qadeer, G Rabbani… - International journal of …, 2014 - Taylor & Francis
Over the past two decades, there has been considerable research interest in the use of
nanoparticles in the study of protein and peptide aggregation, and of amyloid-related …

Multifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases

M Mistretta, A Farini, Y Torrente, C Villa - Brain, 2023 - academic.oup.com
Neurodegenerative diseases are a major global health burden particularly with the
increasing ageing population. Hereditary predisposition and environmental risk factors …

Nanomaterials for reducing amyloid cytotoxicity

M Zhang, X Mao, Y Yu, CX Wang, YL Yang… - Advanced …, 2013 - Wiley Online Library
This review is intended to reflect the recent progress on therapeutic applications of
nanomaterials in amyloid diseases. The progress on anti‐amyloid functions of various …

Nanotechnology-based drug delivery systems for targeting, imaging and diagnosis of neurodegenerative diseases

S Bozdağ Pehlivan - Pharmaceutical research, 2013 - Springer
Neurodegenerative disorders are becoming prevalent with the increasing age of the general
population. A number of difficulties have emerged for the potential treatment of …

Dendrimers in neurodegenerative diseases

MD Pérez-Carrión, I Posadas - Processes, 2023 - mdpi.com
Neurodegenerative diseases (NDs), such as Parkinson's Disease (PD), Alzheimer's Disease
(AD), Multiple Sclerosis (MS) and amyotrophic lateral sclerosis (ALS), are characterized by …

Small molecule modulators of alpha-synuclein aggregation and toxicity: Pioneering an emerging arsenal against Parkinson's disease

IA Ahanger, TA Dar - Ageing Research Reviews, 2024 - Elsevier
Parkinson's disease (PD) is primarily characterized by loss of dopaminergic neurons in the
substantia nigra pars compacta region of the brain and accumulation of aggregated forms of …

Use of polyamidoamine dendrimers in brain diseases

M Florendo, A Figacz, B Srinageshwar, A Sharma… - Molecules, 2018 - mdpi.com
Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise
nanomolecules available today, which have promising applications for the treatment of brain …