Mitochondrial and metabolic dysfunction in ageing and age-related diseases

JA Amorim, G Coppotelli, AP Rolo… - Nature Reviews …, 2022 - nature.com
Organismal ageing is accompanied by progressive loss of cellular function and systemic
deterioration of multiple tissues, leading to impaired function and increased vulnerability to …

[HTML][HTML] Resveratrol for cancer therapy: Challenges and future perspectives

B Ren, MXY Kwah, C Liu, Z Ma, MK Shanmugam… - Cancer letters, 2021 - Elsevier
Abstract Resveratrol (3, 4', 5-trihydroxy-trans-stilbene) has been expected to ameliorate
cancer and foster breakthroughs in cancer therapy. Despite thousands of preclinical studies …

Resveratrol: A double-edged sword in health benefits

B Salehi, AP Mishra, M Nigam, B Sener, M Kilic… - Biomedicines, 2018 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

Polyphenols as potent epigenetics agents for cancer

P Rajendran, SA Abdelsalam, K Renu… - International journal of …, 2022 - mdpi.com
Human diseases such as cancer can be caused by aberrant epigenetic regulation.
Polyphenols play a major role in mammalian epigenome regulation through mechanisms …

Effect of resveratrol and pterostilbene on aging and longevity

YR Li, S Li, CC Lin - Biofactors, 2018 - Wiley Online Library
Over the past years, several studies have found that foods rich in polyphenols protect
against age‐related disease, such as atherosclerosis, cardiovascular disease, cancer …

Benefits and implications of resveratrol supplementation on microbiota modulations: a systematic review of the literature

AD Inchingolo, G Malcangi, AM Inchingolo… - International Journal of …, 2022 - mdpi.com
Resveratrol is a polyphenol that has been shown to possess many applications in different
fields of medicine. This systematic review has drawn attention to the axis between …

Effects of resveratrol, curcumin and quercetin supplementation on bone metabolism—a systematic review

AD Inchingolo, AM Inchingolo, G Malcangi, P Avantario… - Nutrients, 2022 - mdpi.com
Phenolic compounds are natural phytochemicals that have recently reported numerous
health benefits. Resveratrol, curcumin, and quercetin have recently received the most …

The beneficial effects of principal polyphenols from green tea, coffee, wine, and curry on obesity

T Ohishi, R Fukutomi, Y Shoji, S Goto, M Isemura - Molecules, 2021 - mdpi.com
Several epidemiological studies and clinical trials have reported the beneficial effects of
green tea, coffee, wine, and curry on human health, with its anti-obesity, anti-cancer, anti …

[HTML][HTML] Mitochondrial dynamics and transport in Alzheimer's disease

PJ Flannery, E Trushina - Molecular and Cellular Neuroscience, 2019 - Elsevier
Mitochondrial dysfunction is now recognized as a contributing factor to the early pathology of
multiple human conditions including neurodegenerative diseases. Mitochondria are …

[HTML][HTML] Research progress on classification, sources and functions of dietary polyphenols for prevention and treatment of chronic diseases

W Li, H Chen, B Xu, Y Wang, C Zhang, Y Cao… - Journal of Future …, 2023 - Elsevier
Dietary polyphenols are the most abundant antioxidants in daily diet and widely distributed
in plants and plant-based foods, including vegetables, fruits, cereals, nuts, and beverages …