Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Frontotemporal dementia refers to a group of neurodegenerative disorders characterized by
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …

Amyotrophic lateral sclerosis (ALS) is a progressive and fatal neurological disease affecting
both upper and lower motor neurons. In the United States alone, there are 16,000–20,000 …

Neurodegenerative diseases are a group of nervous system conditions characterised
pathologically by the abnormal deposition of protein throughout the brain and spinal cord …

Recent progress in the research for underlying mechanisms in neurodegenerative diseases,
including Alzheimer disease (AD), Parkinson disease (PD), and amyotrophic lateral …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by
progressive degeneration of upper and lower motor neurons. The heterogeneous nature of …

The interaction of neurotrophins with their receptors is involved in the pathogenesis and
progression of various neurological diseases, including Alzheimer's disease, Parkinson's …

The discovery of the neurotrophins and their potent survival and trophic effects led to great
enthusiasm about their therapeutic potential to rescue dying neurons in neurodegenerative …

Background: Amyotrophic lateral sclerosis (ALS) is a progressive and fatal
neurodegenerative disorder of the human motor system. Neuroinflammation appears to be …

Objective: p75 neurotrophin receptor (p75NTR) is associated with the pathogenesis of
amyotrophic lateral sclerosis (ALS). However, its role is not fully understood. The aim of this …