4‐Isoxazolines: Scaffolds for Organic Synthesis

TMVD Pinho e Melo - European Journal of Organic Chemistry, 2010 - Wiley Online Library
This review provides coverage of the more relevant contributions to the synthesis and
reactivity of 4‐isoxazolines (2, 3‐dihydroisoxazoles). The richness of the reactivity of these …

A molecular electron density theory study for [3+ 2] cycloaddition reactions of 1‐pyrroline‐1‐oxide with disubstituted acetylenes leading to bicyclic 4‐isoxazolines

HA Mohammad‐Salim, N Acharjee… - … Journal of Quantum …, 2021 - Wiley Online Library
Abstract The [3+ 2] cycloaddition (32CA) reactions of 1‐pyrroline‐1‐oxide with acetylene
and with a series of four symmetrically disubstituted acetylenes (XC≡ CX, X= CH3, NH2 …

Enantioselective Synthesis of 4‐Isoxazolines by 1, 3‐Dipolar Cycloadditions of Nitrones to Alkynals Catalyzed by Fluorodiphenylmethylpyrrolidines

J Aleman, A Fraile, L Marzo, JLG Ruano… - Advanced Synthesis …, 2012 - Wiley Online Library
Abstract The first organocatalytic enantioselective 1, 3‐dipolar reaction between nitrones
and alkynals catalyzed by (S)‐2‐(fluorodiphenylmethyl) pyrrolidine to give 4‐isoxazolines …

Asymmetric Construction of 2,3-Dihydroisoxazoles via an Organocatalytic Formal [3 + 2] Cycloaddition of Enynes with N-Hydroxylamines

W Li, X Yu, Z Yue, J Zhang - Organic letters, 2016 - ACS Publications
An organocatalytic asymmetric formal [3+ 2] cycloaddition of enynones with N-
hydroxylamines has been described. A newly designed multifunctional organocatalyst was …

Synthesis of 4-Isoxazolines through Gold(I)-Catalyzed Cyclization of Propargylic N-Hydroxylamines

B Chandrasekhar, S Ahn, JS Ryu - The Journal of Organic …, 2016 - ACS Publications
New catalytic methods for the synthesis of 4-isoxazolines have been developed via catalytic
intramolecular cyclizations of propargylic N-hydroxylamines. The reactions proceed rapidly …

[HTML][HTML] Synthesis of spirocyclic Δ 4-isoxazolines via [3+ 2] cycloaddition of indanone-derived ketonitrones with alkynes

Y Liu, J Liu, YY Liu, B Tang, H Lin, Y Li, L Zhang - RSC advances, 2021 - pubs.rsc.org
A [3+ 2] cycloaddition of indanone-derived nitrones and alkynes under mild conditions is
developed, allowing facile synthesis of spirocyclicindenyl isoxazolines with structural …

One pot synthesis of optically active 4-isoxazolines by asymmetric addition of alkynylzinc reagents to nitrones followed by cyclization

小林正和, 宇梶裕, 猪股勝彦 - 2009 - kanazawa-u.repo.nii.ac.jp
One pot synthesis of optically active 4-isoxazolines was achieved by asymmetric addition of
alkynylzinc reagents to nitrones utilizing di (t-butyl)(R, R)-tartrate as a chiral auxiliary …

Hepatoprotective action of prostaglandin A2 analogs under CCl4‐induced liver injury in vitro

AI Hubich, AY Bondar, TU Kastsiuk… - Hepatology …, 2007 - Wiley Online Library
Aim: The cytoprotective effects of six novel synthetic prostaglandin A2 analogs against
carbon tetrachloride (CCl4) as a toxic agent were studied with isolated rat liver hepatocytes …

Synthèse énantiosélective d'aminoacides disubstitués polyfonctionnels via cycloaddition dipolaire d'α-carboxy cétonitrones

KBA Achich - 2016 - theses.hal.science
Lors de ces travaux de thèse, nous nous sommes intéressés au développement de deux
voies différentes de cycloaddition dipolaire-1, 3 (CD-1, 3) asymétrique pour accéder à des …

[PDF][PDF] Биохимия биологически активных веществ

БИОХИМИЯ БИОЛОГИЧЕСКИ АКТИВНЫХ ВЕЩЕСТВ Мелатонин и серотонин Серото Page
1 Биология 73 УДК 577.1 ИВСЕМАК, ВПКУРЧЕНКО, МВШОЛУХ БИОХИМИЯ …