The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI

Y Zhou, C Bie, PCM van Zijl, NN Yadav - NMR in biomedicine, 2023 - Wiley Online Library
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …

Review and consensus recommendations on clinical APT‐weighted imaging approaches at 3T: application to brain tumors

J Zhou, M Zaiss, L Knutsson, PZ Sun… - Magnetic resonance …, 2022 - Wiley Online Library
Amide proton transfer‐weighted (APTw) MR imaging shows promise as a biomarker of brain
tumor status. Currently used APTw MRI pulse sequences and protocols vary substantially …

Correction of B1‐inhomogeneities for relaxation‐compensated CEST imaging at 7 T

J Windschuh, M Zaiss, JE Meissner… - NMR in …, 2015 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging of endogenous agents in vivo is
influenced by direct water proton saturation (spillover) and semi‐solid macromolecular …

Relaxation-compensated CEST-MRI of the human brain at 7 T: unbiased insight into NOE and amide signal changes in human glioblastoma

M Zaiss, J Windschuh, D Paech, JE Meissner, S Burth… - Neuroimage, 2015 - Elsevier
Endogenous chemical exchange saturation transfer (CEST) effects of protons resonating
near to water protons are always diluted by competing effects such as direct water saturation …

Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T

D Paech, J Windschuh, J Oberhollenzer… - Neuro …, 2018 - academic.oup.com
Background Early identification of prognostic superior characteristics in glioma patients such
as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase …

7 Tesla and beyond: advanced methods and clinical applications in magnetic resonance imaging

T Platt, ME Ladd, D Paech - Investigative radiology, 2021 - journals.lww.com
Ultrahigh magnetic fields offer significantly higher signal-to-noise ratio, and several
magnetic resonance applications additionally benefit from a higher contrast-to-noise ratio …

Downfield‐NOE‐suppressed amide‐CEST‐MRI at 7 Tesla provides a unique contrast in human glioblastoma

M Zaiss, J Windschuh, S Goerke… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose The chemical exchange saturation transfer (CEST) effect observed in brain tissue
in vivo at the frequency offset 3.5 ppm downfield of water was assigned to amide protons of …

[HTML][HTML] Neuroimaging at 7 Tesla: a pictorial narrative review

T Okada, K Fujimoto, Y Fushimi, T Akasaka… - … imaging in medicine …, 2022 - ncbi.nlm.nih.gov
Abstract Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is
rapidly gaining popularity after being approved for clinical use in the European Union and …

Relaxation-compensated amide proton transfer (APT) MRI signal intensity is associated with survival and progression in high-grade glioma patients

D Paech, C Dreher, S Regnery, JE Meissner… - European …, 2019 - Springer
Objectives The purpose of this study was to investigate the association of relaxation-
compensated chemical exchange saturation transfer (CEST) MRI with overall survival (OS) …

Whole‐brain amide proton transfer (APT) and nuclear overhauser enhancement (NOE) imaging in glioma patients using low‐power steady‐state pulsed chemical …

HY Heo, CK Jones, J Hua, N Yadav… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose To explore the relationship of amide proton transfer (APT) and nuclear Overhauser
enhancement (NOE) signal intensities with respect to different World Health Organization …