Hyperglycaemia in people with and without diabetes admitted to the hospital is associated
with a substantial increase in morbidity, mortality, and health-care costs. Professional …

Doxorubicin is a commonly used chemotherapeutic agent for the treatment of a range of
cancers, but despite its success in improving cancer survival rates, doxorubicin is cardiotoxic …

Metformin has been extensively used for the treatment of type 2 diabetes, and it may also
promote healthy aging. Despite its widespread use and versatility, metformin's mechanisms …

The prevalence of diabetes and its related complications are increasing significantly
globally. Collected evidence suggested that several genetic and environmental factors …

Adults aged 65 years and older are the fastest growing segment of the US population, and
their number is expected to double to 89 million between 2010 and 2050. The prevalence of …

Abstract Purpose of Review Hyperglycemia contributes to a significant increase in morbidity,
mortality, and healthcare costs in the hospital. Professional associations recommend insulin …

Diabetes mellitus is associated with a high risk of developing gastric cancer (GC). Metformin,
which is conventionally used to treat type 2 diabetes, induces AMP-activated protein kinase …

Metformin (MF) accumulation during acute kidney injury is associated with high anion gap
lactic acidosis type B (MF-associated lactic acidosis, MALA), a serious medical condition …

Abstract Introduction and Objectives There is increasing evidence to suggest that
therapeutic doses of metformin are unlikely to cause lactic acidosis. The aims of this …

In Brief Hyperglycemia in the hospital setting affects 38–46% of noncritically ill hospitalized
patients. Evidence from observational studies indicates that inpatient hyperglycemia, in …