[HTML][HTML] Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases

Y Song, J Liu, K Zhao, L Gao, J Zhao - Cell metabolism, 2021 - cell.com
High levels of cholesterol are generally considered to be associated with atherosclerosis. In
the past two decades, however, a number of studies have shown that excess cholesterol …

An overview of lipid metabolism and nonalcoholic fatty liver disease

K Pei, T Gui, D Kan, H Feng, Y Jin… - BioMed Research …, 2020 - Wiley Online Library
The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major
abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or …

Nutritional importance of carotenoids and their effect on liver health: A review

LI Elvira-Torales, J García-Alonso, MJ Periago-Castón - Antioxidants, 2019 - mdpi.com
The consumption of carotenoids has beneficial effects on health, reducing the risk of certain
forms of cancer, cardiovascular diseases, and macular degeneration, among others. The …

Ezetimibe combination therapy with statin for non-alcoholic fatty liver disease: an open-label randomized controlled trial (ESSENTIAL study)

Y Cho, H Rhee, Y Kim, M Lee, BW Lee, ES Kang… - BMC medicine, 2022 - Springer
Background The effect of ezetimibe, Niemann-Pick C1-like 1 inhibitor, on liver fat is not
clearly elucidated. Our primary objective was to evaluate the efficacy of ezetimibe plus …

Anti-inflammatory and anticancer effects of microalgal carotenoids

J Ávila-Román, S García-Gil, A Rodríguez-Luna… - Marine Drugs, 2021 - mdpi.com
Acute inflammation is a key component of the immune system's response to pathogens, toxic
agents, or tissue injury, involving the stimulation of defense mechanisms aimed to removing …

The molecular and mechanistic insights based on gut–liver axis: nutritional target for non-alcoholic fatty liver disease (NAFLD) improvement

Y Ji, Y Yin, L Sun, W Zhang - International journal of molecular sciences, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is recognized as the most frequent classification of
liver disease around the globe. Along with the sequencing technologies, gut microbiota has …

The use of statins alone, or in combination with pioglitazone and other drugs, for the treatment of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and …

VG Athyros, TK Alexandrides, H Bilianou… - Metabolism, 2017 - Elsevier
Non-alcoholic fatty liver disease (NAFLD), the most common liver disease, is characterized
by accumulation of fat (> 5% of the liver tissue), in the absence of alcohol abuse or other …

Statin use is associated with lower prevalence of advanced liver fibrosis in patients with type 2 diabetes

S Ciardullo, G Perseghin - Metabolism, 2021 - Elsevier
Background Patients with type 2 diabetes (T2D) are at increased risk of both cardiovascular
disease (CVD) and advanced liver fibrosis related to non-alcoholic fatty liver disease …

The role of carotenoids in the prevention and treatment of cardiovascular disease–Current state of knowledge

B Kulczyński, A Gramza-Michałowska… - Journal of Functional …, 2017 - Elsevier
Cardiovascular diseases constitute a significant public health problem. It is estimated that
they cause approx. 30% all deaths worldwide. Many factors are of importance for the …

Dual role of reactive oxygen species in muscle function: can antioxidant dietary supplements counteract age-related sarcopenia?

S Damiano, E Muscariello, G La Rosa… - International journal of …, 2019 - mdpi.com
Sarcopenia is characterized by the progressive loss of skeletal muscle mass and strength. In
older people, malnutrition and physical inactivity are often associated with sarcopenia, and …