[HTML][HTML] Neuropsychiatric lupus: new mechanistic insights and future treatment directions

N Schwartz, AD Stock, C Putterman - Nature Reviews Rheumatology, 2019 - nature.com
Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

[HTML][HTML] Neuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers

H Jeltsch-David, S Muller - Nature Reviews Neurology, 2014 - nature.com
Systemic lupus erythematosus (SLE) is a complex clinical syndrome, elements of which
remain poorly understood. Although recognized over 140 years ago when Kaposi recorded …

[HTML][HTML] Diagnosis and management of neuropsychiatric SLE

JG Hanly - Nature Reviews Rheumatology, 2014 - nature.com
Nervous system involvement in systemic lupus erythematosus (SLE) can manifest as a
range of neurological and psychiatric features, which are classified using the ACR case …

The management of neuropsychiatric lupus in the 21st century: still so many unmet needs?

M Govoni, JG Hanly - Rheumatology, 2020 - academic.oup.com
Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

Autoinflammation and autoimmunity: bridging the divide

A Doria, M Zen, S Bettio, M Gatto, N Bassi, L Nalotto… - Autoimmunity …, 2012 - Elsevier
As soon as autoinflammatory diseases (AIDs) emerged as new entities, they have been
linked to the well known world of autoimmunity. In fact, AIDs and systemic autoimmune …

The diagnosis and clinical management of the neuropsychiatric manifestations of lupus

M Govoni, A Bortoluzzi, M Padovan, E Silvagni… - Journal of …, 2016 - Elsevier
Neuropsychiatric (NP) involvement in Systemic Lupus Erythematosus (SLE), can be a
severe and troubling manifestation of the disease that heavily impacts patient's health …

Performance of antinuclear antibodies for classifying systemic lupus erythematosus: a systematic literature review and meta‐regression of diagnostic data

N Leuchten, A Hoyer, R Brinks, M Schoels… - Arthritis care & …, 2018 - Wiley Online Library
Objective To review the published literature on the performance of indirect
immunofluorescence (IIF)–HE p‐2 antinuclear antibody (ANA) testing for classification of …

Development and validation of a new algorithm for attribution of neuropsychiatric events in systemic lupus erythematosus

A Bortoluzzi, CA Scire, S Bombardieri, L Caniatti… - …, 2015 - academic.oup.com
Objective. The aim of this study was to develop and validate an algorithm to assist the
attribution of neuropsychiatric (NP) events to underlying disease in SLE patients. Methods …

Prevalence, risk factors, and impact on mortality of neuropsychiatric lupus: a prospective, single-center study

GY Ahn, D Kim, S Won, ST Song, HJ Jeong… - Lupus, 2018 - journals.sagepub.com
Objective The objective of this paper is to identify the prevalence, risk factors, and impact on
mortality of neuropsychiatric systemic lupus erythematosus (NPSLE). Methods Patients from …

The chronic damage in systemic lupus erythematosus is driven by flares, glucocorticoids and antiphospholipid antibodies: results from a monocentric cohort

F Conti, F Ceccarelli, C Perricone, I Leccese… - Lupus, 2016 - journals.sagepub.com
Objectives Literature data suggest a significantly higher mortality in patients affected by
systemic lupus erythematosus (SLE) developing chronic damage. Therefore, damage …