Clinical characteristics, pathophysiology, and management of noncentral nervous system cancer‐related cognitive impairment in adults

JS Wefel, SR Kesler, KR Noll… - CA: a cancer journal for …, 2015 - Wiley Online Library
Answer questions and earn CME/CNE Over the past few decades, a body of research has
emerged confirming what many adult patients with noncentral nervous system cancer have …

Chemotherapy-related cognitive dysfunction

JS Wefel, SB Schagen - Current neurology and neuroscience reports, 2012 - Springer
Many cancer patients develop treatment-related cognitive dysfunction that affects their
quality of life and can result in diminished functional independence. There is an emerging …

Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity

U Amstutz, TK Froehlich, CR Largiadèr - Pharmacogenomics, 2011 - Taylor & Francis
The importance of polymorphisms in the dihydropyrimidine dehydrogenase (DPD) gene
(DPYD) for the prediction of severe toxicity in 5-fluorouracil (5-FU) based chemotherapy has …

Neurologic complications of chemotherapy agents

G Kannarkat, EE Lasher, D Schiff - Current opinion in neurology, 2007 - journals.lww.com
Data on prevention and treatment of chemotherapy-induced peripheral neuropathy are
limited. Calcium and magnesium infusions for oxaliplatin administration have the most …

Role of inflammation and oxidative stress in chemotherapy-induced neurotoxicity

P Gupta, TK Makkar, L Goel, M Pahuja - Immunologic Research, 2022 - Springer
Chemotherapeutic agents may adversely affect the nervous system, including the neural
precursor cells as well as the white matter. Although the mechanisms are not completely …

Neurotoxicity of antineoplastic drugs: Mechanisms, susceptibility, and neuroprotective strategies

C Pellacani, G Eleftheriou - Advances in Medical Sciences, 2020 - Elsevier
This review summarizes the adverse effects on the central and/or peripheral nervous
systems that may occur in response to antineoplastic drugs. In particular, we describe the …

Cognitive changes related to cancer therapy

TD Vannorsdall - Medical Clinics, 2017 - medical.theclinics.com
It is estimated that more than 1 in 3 individuals will be diagnosed with cancer over their
lifetimes. 1 Advances in treatment have resulted in a growing population of cancer survivors; …

Chemobrain: A review on mechanistic insight, targets and treatments

V Rao, R Bhushan, P Kumari, SP Cheruku… - Advances in cancer …, 2022 - Elsevier
Chemo-brain refers to the thinking and memory problems that occur in cancer patients
during and after chemotherapy. It is also known as cognitive dysfunction or chemo-fog. Risk …

Neurological complications of chemotherapy to the central nervous system

HB Newton - Handbook of clinical neurology, 2012 - Elsevier
One of the most common complications of chemotherapeutic drugs is toxicity to the central
nervous system (CNS). This toxicity can manifest in many ways, including encephalopathy …

Neurologic complications of chemotherapy and other newer and experimental approaches

R Soffietti, E Trevisan, R Rudà - Handbook of clinical neurology, 2014 - Elsevier
Neurologic complications of conventional cytototxic agents as well as those from
monoclonal antibodies and targeted therapies are increasingly observed in patients with …