Cryoprotectants: A review of the actions and applications of cryoprotective solutes that modulate cell recovery from ultra-low temperatures

GD Elliott, S Wang, BJ Fuller - Cryobiology, 2017 - Elsevier
Cryopreservation has become a central technology in many areas of clinical medicine,
biotechnology, and species conservation within both plant and animal biology …

Ice-binding proteins and their function

M Bar Dolev, I Braslavsky… - Annual review of …, 2016 - annualreviews.org
Ice-binding proteins (IBPs) are a diverse class of proteins that assist organism survival in the
presence of ice in cold climates. They have different origins in many organisms, including …

From ice-binding proteins to bio-inspired antifreeze materials

IK Voets - Soft Matter, 2017 - pubs.rsc.org
Ice-binding proteins (IBP) facilitate survival under extreme conditions in diverse life forms.
IBPs in polar fishes block further growth of internalized environmental ice and inhibit ice …

Blocking rapid ice crystal growth through nonbasal plane adsorption of antifreeze proteins

LLC Olijve, K Meister, AL DeVries… - Proceedings of the …, 2016 - National Acad Sciences
Antifreeze proteins (AFPs) are a unique class of proteins that bind to growing ice crystal
surfaces and arrest further ice growth. AFPs have gained a large interest for their use in …

Control strategies of ice nucleation, growth, and recrystallization for cryopreservation

M Lin, H Cao, J Li - Acta Biomaterialia, 2023 - Elsevier
The cryopreservation of biomaterials is fundamental to modern biotechnology and
biomedicine, but the biggest challenge is the formation of ice, resulting in fatal cryoinjury to …

Crystal growth with macromolecular additives

AG Shtukenberg, MD Ward, B Kahr - Chemical reviews, 2017 - ACS Publications
Interactions of macromolecules with growing crystalline surfaces play an important role in
biomineralization, determine survival of some organisms at low temperatures, and offer a …

[HTML][HTML] Ice-binding proteins in plants

M Bredow, VK Walker - Frontiers in plant science, 2017 - frontiersin.org
Sub-zero temperatures put plants at risk of damage associated with the formation of ice
crystals in the apoplast. Some freeze-tolerant plants mitigate this risk by expressing ice …

Ice recrystallization inhibition by amino acids: The curious case of alpha-and beta-alanine

MT Warren, I Galpin, F Bachtiger… - The journal of …, 2022 - ACS Publications
Extremophiles produce macromolecules which inhibit ice recrystallization, but there is
increasing interest in discovering and developing small molecules that can modulate ice …

Crystal structure of an insect antifreeze protein and its implications for ice binding

A Hakim, JB Nguyen, K Basu, DF Zhu, D Thakral… - Journal of Biological …, 2013 - ASBMB
Antifreeze proteins (AFPs) help some organisms resist freezing by binding to ice crystals
and inhibiting their growth. The molecular basis for how these proteins recognize and bind …

A supramolecular ice growth inhibitor

R Drori, C Li, C Hu, P Raiteri, AL Rohl… - Journal of the …, 2016 - ACS Publications
Safranine O, a synthetic dye, was found to inhibit growth of ice at millimolar concentrations
with an activity comparable to that of highly evolved antifreeze glycoproteins. Safranine …