Emerging landscape of molecular interaction networks: Opportunities, challenges and prospects
Network biology finds application in interpreting molecular interaction networks and
providing insightful inferences using graph theoretical analysis of biological systems. The …
providing insightful inferences using graph theoretical analysis of biological systems. The …
Mechanism-centric approaches for biomarker detection and precision therapeutics in cancer
CY Yu, A Mitrofanova - Frontiers in Genetics, 2021 - frontiersin.org
Biomarker discovery is at the heart of personalized treatment planning and cancer precision
therapeutics, encompassing disease classification and prognosis, prediction of treatment …
therapeutics, encompassing disease classification and prognosis, prediction of treatment …
Identification and validation of a novel DNA damage and DNA repair related genes based signature for colon cancer prognosis
X Wang, S Xu, W Wang, S Piao, X Mao, X Zhou… - Frontiers in …, 2021 - frontiersin.org
Backgrounds: Colorectal cancer (CRC) with high incidence, has the third highest mortality of
tumors. DNA damage and repair influence a variety of tumors. However, the role of these …
tumors. DNA damage and repair influence a variety of tumors. However, the role of these …
Translational Bioinformatics Applied to the study of Complex diseases
MC Casotti, DD Meira, LNR Alves, BGO Bessa… - Genes, 2023 - mdpi.com
Translational Bioinformatics (TBI) is defined as the union of translational medicine and
bioinformatics. It emerges as a major advance in science and technology by covering …
bioinformatics. It emerges as a major advance in science and technology by covering …
Combinatorial analyses reveal cellular composition changes have different impacts on transcriptomic changes of cell type specific genes in Alzheimer's Disease
Alzheimer's disease (AD) brains are characterized by progressive neuron loss and gliosis.
Previous studies of gene expression using bulk tissue samples often fail to consider …
Previous studies of gene expression using bulk tissue samples often fail to consider …
Prediction of Prognosis, Immunotherapy and Chemotherapy with an Immune-Related Risk Score Model for Endometrial Cancer
W Wei, B Ye, Z Huang, X Mu, J Qiao, P Zhao, Y Jiang… - Cancers, 2023 - mdpi.com
Simple Summary Endometrial cancer (EC) is one of the most common gynecologic cancers.
However, its clinical therapy remains unsatisfying due to the lack of effective treatment …
However, its clinical therapy remains unsatisfying due to the lack of effective treatment …
[HTML][HTML] Acidic leucine-rich nuclear phosphoprotein-32A expression contributes to adverse outcome in acute myeloid leukemia
S Huang, Z Huang, C Ma, L Luo, YF Li… - Annals of …, 2020 - ncbi.nlm.nih.gov
Background Acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) is a novel regulator
of histone H3 acetylation and promotes leukemogenesis in acute myeloid leukemia (AML) …
of histone H3 acetylation and promotes leukemogenesis in acute myeloid leukemia (AML) …
Co-PATHOgenex web application for assessing complex stress responses in pathogenic bacteria
Pathogenic bacteria encounter various stressors while residing in the host. They respond
through intricate mechanisms of gene expression regulation, ensuring their survival and …
through intricate mechanisms of gene expression regulation, ensuring their survival and …
ALRIGMR: Adaptive logistic regression via integrating gene mutation and RNA-seq for liver cancer diagnosis
J Li, F Cao, H Zhang - Biomedical Signal Processing and Control, 2024 - Elsevier
RNA-seq is often used for early accurate diagnosis and related gene screening of liver
cancer, significantly improving patients' survival rates. Popular diagnostic methods based on …
cancer, significantly improving patients' survival rates. Popular diagnostic methods based on …
Aberrant Chloride Intracellular Channel 4 Expression Is Associated With Adverse Outcome in Cytogenetically Normal Acute Myeloid Leukemia
S Huang, Z Huang, P Chen, C Feng - Frontiers in oncology, 2020 - frontiersin.org
Background and Methods: Acute myeloid leukemia (AML), which starts in the bone marrow,
is a group of hematopoietic stem cell disorders. Chloride intracellular channel 4 (CLIC4) is …
is a group of hematopoietic stem cell disorders. Chloride intracellular channel 4 (CLIC4) is …