Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune
response in a very complex and flowery manner. The history of host-parasite co-evolution …

Chagas disease is caused by the protozoan Trypanosoma cruzi. The parasite reaches the
secondary lymphoid organs, the heart, skeletal muscles, neurons in the intestine and …

SciELO - Brazil - Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com
Cardiomiopatia da Doença de Chagas – 2023 Diretriz da SBC sobre Diagnóstico e Tratamento …

Members of the IL-17 cytokine family play an important role in protection against pathogens
through the induction of different effector mechanisms. We determined that IL-17A, IL-17E …

Live attenuated Leishmania donovani parasites such as LdCen−/− have been shown elicit
protective immunity against leishmanial infection in mice and hamster models. Previously …

Trypanosoma cruzi is a remarkably versatile parasite. It can parasitize almost any nucleated
cell type and naturally infects hundreds of mammal species across much of the Americas. In …

In mammals, chronic diseases resulting from infectious agents have been associated with
functional T cell response deficiency, a high frequency of terminally differentiated T cells, the …

Current understanding of key cellular pathways, which are activated by the interaction
between T. cruzi and host immunity, is crucial for controlling T. cruzi infection and also for …

A DC (tripanossomíase americana) é entidade mórbida transmissível, potencialmente fatal,
causada pelo protozoário parasita T. cruzi e que integra o grupo de doenças tropicais …

Background CD8+ T cells have been shown to play a crucial role in Trypanosoma cruzi
infection. Memory CD8+ T cells can be categorised based on their distinct differentiation …