Biology of interleukin-17 and its pathophysiological significance in sepsis
Y Ge, M Huang, Y Yao - Frontiers in immunology, 2020 - frontiersin.org
The interleukin (IL)-17 family includes six structure-related cytokines (A–F). To date, majority
of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases …
of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases …
Cytokine production by human neutrophils: Revisiting the “dark side of the moon”
N Tamassia, F Bianchetto‐Aguilera… - European journal of …, 2018 - Wiley Online Library
Polymorphonuclear neutrophils are the most numerous leucocytes present in human blood,
and function as crucial players in innate immune responses. Neutrophils are indispensable …
and function as crucial players in innate immune responses. Neutrophils are indispensable …
MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape
VD Menachery, A Schäfer… - Proceedings of the …, 2018 - National Acad Sciences
Convergent evolution dictates that diverse groups of viruses will target both similar and
distinct host pathways to manipulate the immune response and improve infection. In this …
distinct host pathways to manipulate the immune response and improve infection. In this …
New players in immunity to tuberculosis: the host microbiome, lung epithelium, and innate immune cells
Tuberculosis (TB) is a highly contagious infection and devastating chronic disease, causing
10.4 million new infections and 1.8 million deaths every year globally. Efforts to control and …
10.4 million new infections and 1.8 million deaths every year globally. Efforts to control and …
Antimicrobial activity of neutrophils against mycobacteria
HA Parker, L Forrester, CD Kaldor, N Dickerhof… - Frontiers in …, 2021 - frontiersin.org
The mycobacterium genus contains a broad range of species, including the human
pathogens M. tuberculosis and M. leprae. These bacteria are best known for their residence …
pathogens M. tuberculosis and M. leprae. These bacteria are best known for their residence …
[HTML][HTML] Yin and yang of interleukin-17 in host immunity to infection
Abstract The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play
important protective roles in host immune response to a variety of infections such as …
important protective roles in host immune response to a variety of infections such as …
Multi-facets of neutrophil extracellular trap in infectious diseases: Moving beyond immunity
Neutrophil extracellular traps (NETs) are networks of extracellular chromosomal DNA fibers,
histones, and cytoplasmic granule proteins. The release of NET components from …
histones, and cytoplasmic granule proteins. The release of NET components from …
A Reappraisal on the Potential Ability of Human Neutrophils to Express and Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It
N Tamassia, F Arruda-Silva, F Calzetti… - Frontiers in …, 2018 - frontiersin.org
Neutrophils are known to perform a series of effector functions that are crucial for the innate
and adaptive responses, including the synthesis and secretion of a variety of cytokines. In …
and adaptive responses, including the synthesis and secretion of a variety of cytokines. In …
Lessons from Bacillus Calmette-Guerin: harnessing trained immunity for vaccine development
ST Pasco, J Anguita - Cells, 2020 - mdpi.com
Vaccine design traditionally focuses on inducing adaptive immune responses against a sole
target pathogen. Considering that many microbes evade innate immune mechanisms to …
target pathogen. Considering that many microbes evade innate immune mechanisms to …
Neutrophil extracellular trap (NET) levels in human plasma are associated with active TB
MC Schechter, K Buac, T Adekambi, S Cagle, J Celli… - PLoS …, 2017 - journals.plos.org
Neutrophils are increasingly associated with tuberculosis (TB) disease. Neutrophil
extracellular traps (NETs), which are released by neutrophils as a host antimicrobial defense …
extracellular traps (NETs), which are released by neutrophils as a host antimicrobial defense …