The interleukin (IL)-17 family includes six structure-related cytokines (A–F). To date, majority
of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases …

Polymorphonuclear neutrophils are the most numerous leucocytes present in human blood,
and function as crucial players in innate immune responses. Neutrophils are indispensable …

Convergent evolution dictates that diverse groups of viruses will target both similar and
distinct host pathways to manipulate the immune response and improve infection. In this …

Tuberculosis (TB) is a highly contagious infection and devastating chronic disease, causing
10.4 million new infections and 1.8 million deaths every year globally. Efforts to control and …

The mycobacterium genus contains a broad range of species, including the human
pathogens M. tuberculosis and M. leprae. These bacteria are best known for their residence …

Abstract The interleukin-17 (IL-17) family cytokines, such as IL-17A and IL-17F, play
important protective roles in host immune response to a variety of infections such as …

Neutrophil extracellular traps (NETs) are networks of extracellular chromosomal DNA fibers,
histones, and cytoplasmic granule proteins. The release of NET components from …

Neutrophils are known to perform a series of effector functions that are crucial for the innate
and adaptive responses, including the synthesis and secretion of a variety of cytokines. In …

Vaccine design traditionally focuses on inducing adaptive immune responses against a sole
target pathogen. Considering that many microbes evade innate immune mechanisms to …

Neutrophils are increasingly associated with tuberculosis (TB) disease. Neutrophil
extracellular traps (NETs), which are released by neutrophils as a host antimicrobial defense …