Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

The pyrazole nucleus is an aromatic azole heterocycle with two adjacent nitrogen atoms.
Pyrazole derivatives have exhibited a broad spectrum of biological activities, and approved …

Nitrogen-containing heterocyclic compounds and their derivatives have historically been
invaluable as a source of therapeutic agents. Pyrazole, which has two nitrogen atoms and …

Pyrazole is a five-membered aromatic heterocyclic ring with two adjacent nitrogen atoms C 3
H 3 N 2 H. The presence of this nucleus in pharmacological agents of various therapeutic …

The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …

Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …

Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …

Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …