Randomized controlled trials–a matter of design

PM Spieth, AS Kubasch, AI Penzlin… - Neuropsychiatric …, 2016 - Taylor & Francis
Randomized controlled trials (RCTs) are the hallmark of evidence-based medicine and form
the basis for translating research data into clinical practice. This review summarizes …

Ischemic posterior circulation stroke: a review of anatomy, clinical presentations, diagnosis, and current management

A Nouh, J Remke, S Ruland - Frontiers in neurology, 2014 - frontiersin.org
Posterior circulation strokes represent approximately 20% of all ischemic strokes (,). In
contrast to the anterior circulation, several differences in presenting symptoms, clinical …

[HTML][HTML] Trial of thrombectomy 6 to 24 hours after stroke due to basilar-artery occlusion

TG Jovin, C Li, L Wu, C Wu, J Chen… - … England Journal of …, 2022 - Mass Medical Soc
Background The effects and risks of endovascular thrombectomy 6 to 24 hours after stroke
onset due to basilar-artery occlusion have not been extensively studied. Methods In a trial …

Endovascular therapy for stroke due to basilar-artery occlusion

LCM Langezaal, EJRJ Van Der Hoeven… - … England Journal of …, 2021 - Mass Medical Soc
Background The effectiveness of endovascular therapy in patients with stroke caused by
basilar-artery occlusion has not been well studied. Methods We randomly assigned patients …

Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial

X Liu, Q Dai, R Ye, W Zi, Y Liu, H Wang, W Zhu… - The Lancet …, 2020 - thelancet.com
Background Previous randomised trials have shown an overwhelming benefit of mechanical
thrombectomy for treating patients with stroke caused by large vessel occlusion of the …

Assessment of endovascular treatment for acute basilar artery occlusion via a nationwide prospective registry

W Zi, Z Qiu, D Wu, F Li, H Liu, W Liu, W Huang… - JAMA …, 2020 - jamanetwork.com
Importance Several randomized clinical trials have recently established the safety and
efficacy of endovascular treatment (EVT) of acute ischemic stroke in the anterior circulation …

Endovascular treatment versus best medical management in acute basilar artery occlusion strokes: results from the ATTENTION multicenter registry

C Tao, AI Qureshi, Y Yin, J Li, R Li, P Xu, J Sun… - Circulation, 2022 - Am Heart Assoc
Background: The authors compare the effectiveness and safety of endovascular treatment
(EVT) versus best medical management (BMM) in strokes attributable to acute basilar artery …

Mechanical recanalization in basilar artery occlusion: the ENDOSTROKE study

OC Singer, J Berkefeld, CH Nolte, G Bohner… - Annals of …, 2015 - Wiley Online Library
Objective A study was undertaken to evaluate clinical and procedural factors associated with
outcome and recanalization in endovascular stroke treatment (EVT) of basilar artery (BA) …

Endovascular treatment for acute basilar artery occlusion: a multicenter randomized controlled trial (ATTENTION)

C Tao, R Li, Y Zhu, S Qun, P Xu… - … Journal of Stroke, 2022 - journals.sagepub.com
Background and hypothesis: Recently, two multicenter randomized controlled trials (RCT)
failed to show a significantly beneficial effect of endovascular treatment (EVT) in patients …

Endovascular thrombectomy for acute basilar artery occlusion: a multicenter retrospective observational study

DH Kang, C Jung, W Yoon, SK Kim… - Journal of the …, 2018 - Am Heart Assoc
Background Despite the recent acceptance of thrombectomy as the standard of care in
patients with acute anterior circulation stroke, the benefits of thrombectomy remain uncertain …