The human stress response
G Russell, S Lightman - Nature reviews endocrinology, 2019 - nature.com
The human stress response has evolved to maintain homeostasis under conditions of real or
perceived stress. This objective is achieved through autoregulatory neural and hormonal …
perceived stress. This objective is achieved through autoregulatory neural and hormonal …
Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility
JK Gjerstad, SL Lightman, F Spiga - Stress, 2018 - Taylor & Francis
The hypothalamic–pituitary–adrenal (HPA) axis is the major neuroendocrine axis regulating
homeostasis in mammals. Glucocorticoid hormones are rapidly synthesized and secreted …
homeostasis in mammals. Glucocorticoid hormones are rapidly synthesized and secreted …
[HTML][HTML] Molecular mechanisms of glucocorticoid-induced insulin resistance
C Beaupere, A Liboz, B Fève, B Blondeau… - International journal of …, 2021 - mdpi.com
Glucocorticoids (GCs) are steroids secreted by the adrenal cortex under the hypothalamic-
pituitary-adrenal axis control, one of the major neuro-endocrine systems of the organism …
pituitary-adrenal axis control, one of the major neuro-endocrine systems of the organism …
Cortisol and DHEA in development and psychopathology
HS Kamin, DA Kertes - Hormones and behavior, 2017 - Elsevier
Dehydroepiandrosterone (DHEA) and cortisol are the most abundant hormones of the
human fetal and adult adrenals released as end products of a tightly coordinated endocrine …
human fetal and adult adrenals released as end products of a tightly coordinated endocrine …
Proteomics reveals the effects of sustained weight loss on the human plasma proteome
PE Geyer, NJ Wewer Albrechtsen… - Molecular systems …, 2016 - embopress.org
Sustained weight loss is a preferred intervention in a wide range of metabolic conditions, but
the effects on an individual's health state remain ill‐defined. Here, we investigate the plasma …
the effects on an individual's health state remain ill‐defined. Here, we investigate the plasma …
An antibody-based molecular switch for continuous small-molecule biosensing
IAP Thompson, J Saunders, L Zheng, AA Hariri… - Science …, 2023 - science.org
We present a generalizable approach for designing biosensors that can continuously detect
small-molecule biomarkers in real time and without sample preparation. This is achieved by …
small-molecule biomarkers in real time and without sample preparation. This is achieved by …
Measuring cortisol in human psychobiological studies
A Levine, O Zagoory-Sharon, R Feldman, JG Lewis… - Physiology & …, 2007 - Elsevier
The steroid cortisol is an extensively studied and important variable in developmental and
other behavioral studies. Cortisol has been assayed by various methods using a range of …
other behavioral studies. Cortisol has been assayed by various methods using a range of …
Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription
DA Stavreva, M Wiench, S John… - Nature cell …, 2009 - nature.com
Studies on glucocorticoid receptor (GR) action typically assess gene responses by long-term
stimulation with synthetic hormones. As corticosteroids are released from adrenal glands in …
stimulation with synthetic hormones. As corticosteroids are released from adrenal glands in …
[HTML][HTML] The glucocorticoid receptor in cardiovascular health and disease
B Liu, TN Zhang, JK Knight, JE Goodwin - Cells, 2019 - mdpi.com
The glucocorticoid receptor is a member of the nuclear receptor family that controls many
distinct gene networks, governing various aspects of development, metabolism …
distinct gene networks, governing various aspects of development, metabolism …