Associations of CYP4A11 gene–gene and gene–smoking interactions with essential hypertension in the male eastern Chinese Han population
H Zhang, L Jin, T Mu, Y Fan, H Zhang… - Clinical and …, 2017 - Taylor & Francis
Objectives: The aim of this study was to investigate the impact of CYP4A11 single-nucleotide
polymorphisms (SNP), additional gene–gene and gene–environment interactions on …
polymorphisms (SNP), additional gene–gene and gene–environment interactions on …
Landscape of Germline Genetic Variants in AGT, MGMT, and TP53 in Mexican Adult Patients with Astrocytoma
JA Carlos-Escalante, L Gomez-Flores-Ramos… - Cellular and Molecular …, 2021 - Springer
Astrocytoma is the most common type of primary brain tumor. The risk factors for astrocytoma
are poorly understood; however, germline genetic variants account for 25% of the risk of …
are poorly understood; however, germline genetic variants account for 25% of the risk of …
CYP4A11 gene T8590C polymorphism is associated with essential hypertension in the male western Chinese Han population
H Yang, Z Fu, Y Ma, D Huang, Q Zhu… - Clinical and …, 2014 - Taylor & Francis
Background: CYP4A11 is a member of the cytochrome P450 enzymes and is responsible for
metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid, a metabolite involved in …
metabolizing arachidonic acid to 20-hydroxyeicosatetraenoic acid, a metabolite involved in …
Risk conferred by tagged SNPs of AGT gene in causing susceptibility to essential hypertension
G Padma, N Swapna, M Mamata… - Clinical and …, 2014 - Taylor & Francis
Introduction: AGT gene harbors several variants of which 21 are found to be in high linkage
disequilibrium as per Hapmap database. Studies delineating the importance of these tagged …
disequilibrium as per Hapmap database. Studies delineating the importance of these tagged …
Role of tagged SNPs of the AGT gene in causing susceptibility to essential hypertension
P Gunda, S Nagalingam, P Tirunilai - Clinical and experimental …, 2016 - Taylor & Francis
Aim: Angiotensinogen (AGT) is one of the candidate genes that has been extensively
investigated for association of its variants with essential hypertension. Studies focusing on …
investigated for association of its variants with essential hypertension. Studies focusing on …
Impact of interactions between risk alleles on clinical endpoints in hypertension
Objective Impairment of the renin-angiotensinogen-aldosterone system (RAAS), one of the
characteristics of essential hypertension (EH), imbalances vascular homeostasis. Despite …
characteristics of essential hypertension (EH), imbalances vascular homeostasis. Despite …
Risk given by AGT polymorphisms in inducing susceptibility to essential hypertension among isolated populations from a remote region of China: A case-control study …
Q Li, L Sun, J Du, P Ran, T Gao… - Journal of the Renin …, 2015 - journals.sagepub.com
Introduction: Hypertension is a serious risk factor affecting up to 30% of the world's
population with a heritability of more than 30–50%. The aim of this study was to investigate …
population with a heritability of more than 30–50%. The aim of this study was to investigate …