In clinical practice, we often deal with patients who suffer from non-alcoholic fatty liver
disease (NAFLD) concurrent with type 2 diabetes mellitus (T2DM). The etiopathogenesis of …

Communication between organs participates in most physiological and pathological events.
Owing to the importance of precise coordination among the liver and virtually all organs in …

Abstract Fetuin-A (Alfa 2-Heremans-Schmid) is a glycoprotein that is mainly synthesized by
hepatocytes and then released into the bloodstream. While fetuin-A, a multifunctional …

Spexin is a novel neuropeptide playing an emerging role in metabolic diseases such as
obesity and diabetes via involvement in energy homeostasis and food intake. The present …

Obesity is characterized by an excessive accumulation of fat leading to a plethora of medical
complications, including coronary artery disease, hypertension, type 2 diabetes mellitus or …

Hepatokines (liver secreted proteins with possible distant action) are emerging potential
players in insulin resistance in type 2 diabetic patients. Here, we explored the effect of a high …

Excessive fatty acids and glucose uptake support the infiltration of adipose tissue (AT) by a
variety of immune cells including neutrophils, pro-inflammatory M1 macrophages, and mast …

There is a high frequency of overweight and obesity in women of reproductive age. Women
who start pregnancy with overweight or obesity have an increased risk of developing …

Background Diabetic kidney disease (DKD) stands as a primary contributor to end-stage
renal disease, associated with heightened mortality in cardiovascular diseases. This study …

Fetuin-A, a plasma multifunctional protein known to play a role in insulin resistance, is
usually presented as a liver secreted protein. However, fetuin-A adipose tissue production …