A G-quadruplex (G4) is a well-known nucleic acid secondary structure comprising guanine-
rich sequences, and has profound implications for various pharmacological and biological …

DNA has the ability to form polymorphic structures like canonical duplex DNA and non-
canonical triplex DNA, Cruciform, Z-DNA, G-quadruplex (G4), i-motifs, and hairpin structures …

The noncanonical guanine-rich DNAs have drawn particular attention to the scientific world
due to their controllable diverse and polymorphic structures. Apart from biological and …

Mitochondria is the cell's energy powerhouse and regulate most of the metabolism process
through the inherent mitochondrial genes (mtDNA). The control of mtDNA replication and …

G-Quadruplex (GQ) nucleic acids are promising therapeutic targets in anticancer research
due to their structural robustness, polymorphism, and gene-regulatory functions. Here, we …

Four new complexes of Cu (II) coordinated to a benzoyl hydrazine Schiff base–[Cu (L1)
Cl](C1),[Cu (L1) Py](C2),[Cu (L2) NO 3](C3),[Cu (L3) NO 3](C4)–were synthesized and …

The presence of the G-quadruplex (G4) structure in the promoter region of the human bcl-2
oncogenes makes it a promising target for developing anti-cancer therapeutics. Bcl-2 …

A series of new benzimidazole-1, 2, 3-triazole hybrid derivatives have been synthesized via
'click'reaction and evaluated for their in vitro cytotoxicity as well as DNA binding affinity. MTT …

Specific sensing and functional tuning of nucleic acid secondary structures remain less
explored to date. Herein, we report a thiazole polyamide TPW that binds specifically to c …

The spectroscopic investigation of the DNA-binding properties of (S)-6, 8-dimethoxy-2-(4′-
methoxy-[1, 1′-biphenyl]-4-yl)-1, 3-dimethyl-3, 4-dihydroisoquinolin-2-ium revealed the …