In this review, we detail the changes and the relevant features that are applied to
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …

Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) represent a rare
diagnosis of the gastro-entero-pancreatic tract. Evidence from the current literature …

This ENETS guidance paper, developed by a multidisciplinary working group, provides up‐
to‐date and practical advice on the diagnosis and management of digestive neuroendocrine …

The neuroendocrine carcinoma of the gastrointestinal system (GIS-NEC) is a rare but highly
malignant neoplasm. We analyzed 115 cases using whole-genome/exome sequencing …

Neuroendocrine neoplasms of the appendix, colon and rectum are classified according to
the most recent WHO classification as neuroendocrine tumors (NET), neuroendocrine …

Over the past 5 years, a number of notable research advances have been made in the field
of neuroendocrine cancer, specifically with regard to neuroendocrine cancer of the …

The cyclic-GMP-AMP synthetase stimulator of interferon genes (cGAS-STING) pathway is a
naturally occurring immune pathway activated by cytosolic DNA. The end products of this …

Histopathological classifications of neuroendocrine neoplasms (NEN) change regularly and
the latest WHO classification published in 2022, which concerns all NEN in the body …

Neuroendocrine neoplasms (NENs) originate from the neuroendocrine cell system, which
may either take the shape of organoid cell aggregations or be composed of dispersed cells …

Background: In gastroenteropancreatic (GEP) high-grade neuroendocrine neoplasms (H-
NENs), Ki-67 threshold of 55% defines three prognosis subclasses: neuroendocrine tumor …