[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Nano based drug delivery systems: recent developments and future prospects

JK Patra, G Das, LF Fraceto, EVR Campos… - Journal of …, 2018 - Springer
Nanomedicine and nano delivery systems are a relatively new but rapidly developing
science where materials in the nanoscale range are employed to serve as means of …

[HTML][HTML] Hyaluronic acid: molecular mechanisms and therapeutic trajectory

RC Gupta, R Lall, A Srivastava, A Sinha - Frontiers in veterinary …, 2019 - frontiersin.org
Hyaluronic acid (also known as hyaluronan or hyaluronate) is naturally found in many
tissues and fluids, but more abundantly in articular cartilage and synovial fluid (SF) …

Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Hyaluronic acid and albumin based nanoparticles for drug delivery

C Lei, XR Liu, QB Chen, Y Li, JL Zhou, LY Zhou… - Journal of Controlled …, 2021 - Elsevier
Albumin, a multifunctional protein, is widely used to prepare nanocarriers. Hyaluronic acid
(HA) is a natural glycosaminoglycan that can specifically bind receptors, such as cluster of …

Hyaluronic acid in ocular drug delivery

X Zhang, D Wei, Y Xu, Q Zhu - Carbohydrate Polymers, 2021 - Elsevier
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

[HTML][HTML] Nanotechnology-based strategies for treatment of ocular disease

Y Weng, J Liu, S Jin, W Guo, X Liang, Z Hu - Acta pharmaceutica sinica B, 2017 - Elsevier
Ocular diseases include various anterior and posterior segment diseases. Due to the unique
anatomy and physiology of the eye, efficient ocular drug delivery is a great challenge to …

Hydrogel biomaterials for application in ocular drug delivery

CR Lynch, PPD Kondiah, YE Choonara… - … in bioengineering and …, 2020 - frontiersin.org
There are many challenges involved in ocular drug delivery. These are a result of the many
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …

Ocular drug delivery: Role of degradable polymeric nanocarriers for ophthalmic application

CH Tsai, PY Wang, IC Lin, H Huang, GS Liu… - International journal of …, 2018 - mdpi.com
Ocular drug delivery has been a major challenge for clinical pharmacologists and
biomaterial scientists due to intricate and unique anatomical and physiological barriers in …

Nanomaterial-based ophthalmic drug delivery

G Xie, S Lin, F Wu, J Liu - Advanced drug delivery reviews, 2023 - Elsevier
The low bioavailability and side effects of conventional drugs for eye disease necessitate the
development of efficient drug delivery systems. Accompanying the developments of …