Sex bias in lymphocytes: Implications for autoimmune diseases

KC Dodd, M Menon - Frontiers in Immunology, 2022 - frontiersin.org
Autoimmune diseases are characterized by a significant sex dimorphism, with women
showing increased susceptibility to disease. This is, at least in part, due to sex-dependent …

Gender specific differences in disease susceptibility: the role of epigenetics

L Migliore, V Nicoli, A Stoccoro - Biomedicines, 2021 - mdpi.com
Many complex traits or diseases, such as infectious and autoimmune diseases, cancer,
xenobiotics exposure, neurodevelopmental and neurodegenerative diseases, as well as the …

Sex bias in autoimmunity

AC Billi, JM Kahlenberg… - Current opinion in …, 2019 - journals.lww.com
Sex bias in autoimmunity : Current Opinion in Rheumatology Sex bias in autoimmunity :
Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …

Genes that escape from X‐chromosome inactivation: Potential contributors to Klinefelter syndrome

MJ Navarro‐Cobos, BP Balaton… - American Journal of …, 2020 - Wiley Online Library
One of the two X chromosomes in females is epigenetically inactivated, thereby
compensating for the dosage difference in X‐linked genes between XX females and XY …

Long non-coding RNA Xist contribution in systemic lupus erythematosus and rheumatoid arthritis

C Bost, MI Arleevskaya, WH Brooks, S Plaza… - Clinical …, 2022 - Elsevier
Growing evidence points towards the role of the long non-coding (lnc)-RNA Xist expressed
in female cells as a predominant key actor for the sex bias observed in systemic lupus …

47XXY and 47XXX in Scleroderma and Myositis

RH Scofield, VM Lewis, J Cavitt… - ACR Open …, 2022 - Wiley Online Library
Objective We undertook this study to examine the X chromosome complement in
participants with systemic sclerosis (SSc) as well as idiopathic inflammatory myopathies …

Nonendocrine mechanisms of sex bias in rheumatic diseases

NC Lambert - Nature Reviews Rheumatology, 2019 - nature.com
Rheumatic diseases affect a wide range of individuals of all ages, but the most common
diseases occur more frequently in women than in men, at ratios of up to ten women to one …

Sex and gender differences in infection and treatments for infectious diseases

SL Klein, CW Roberts - 2015 - Springer
In 1988 I was invited, as an immunologist working on parasites, by the then Editor of
Parasitology Today to debate with the epidemiologist, Don Bundy, the reasons why males …

[PDF][PDF] One year in review 2017: systemic sclerosis

S Barsotti, C Bruni, M Orlandi… - Clin Exp …, 2017 - clinexprheumatol.org
Systemic sclerosis is a rare acquired systemic disease characterised by heterogeneous
evolution and outcome. Each year novel insights into the pathogenesis, diagnosis and …

Epigenetics, pregnancy and autoimmune rheumatic diseases

G Pacini, S Paolino, L Andreoli, A Tincani, M Gerosa… - Autoimmunity …, 2020 - Elsevier
Autoimmune rheumatic diseases (ARDs) are chronic conditions with a striking female
predominance, frequently affecting women of childbearing age. Sex hormones and gender …