Chronic kidney disease (CKD) is a global health problem with rising incidence and
prevalence. Among several pathogenetic mechanisms responsible for disease progression …

CD36 is a type 2 cell surface scavenger receptor widely expressed in many immune and
non-immune cells. It functions as both a signaling receptor responding to DAMPs and …

Obesity and hyperlipidemia are the most prevalent independent risk factors of chronic
kidney disease (CKD), suggesting that lipid accumulation in the renal parenchyma is …

Dyslipidaemia is a hallmark of chronic kidney disease (CKD). The severity of dyslipidaemia
not only correlates with CKD stage but is also associated with CKD-associated …

CD36 (also known as scavenger receptor B2) is a multifunctional receptor that mediates the
binding and cellular uptake of long-chain fatty acids, oxidized lipids and phospholipids …

Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders
of the kidney in various etiologies, which significantly affect human survival and social …

The kidney is a highly metabolic organ and uses high levels of ATP to maintain electrolyte
and acid-base homeostasis and reabsorb nutrients. Energy depletion is a critical factor in …

The term uraemic cardiomyopathy refers to the cardiac abnormalities that are seen in
patients with chronic kidney disease (CKD). Historically, this term was used to describe a …

The Na/K-ATPase (NKA), or Na pump, is a member of the P-type ATPase superfamily. In
addition to pumping ions across cell membrane, it is engaged in assembly of multiple …

Lipid dysmetabolism is one of the main features of diabetes mellitus and manifests by
dyslipidemia as well as the ectopic accumulation of lipids in various tissues and organs …