[HTML][HTML] Mitochondrial heterogeneity in diseases

L Chen, M Zhou, H Li, D Liu, P Liao, Y Zong… - … and Targeted Therapy, 2023 - nature.com
As key organelles involved in cellular metabolism, mitochondria frequently undergo
adaptive changes in morphology, components and functions in response to various …

Mitochondria: A worthwhile object for ultrastructural qualitative characterization and quantification of cells at physiological and pathophysiological states using …

H Duranova, V Valkova, Z Knazicka, L Olexikova… - Acta …, 2020 - Elsevier
Mitochondria are highly dynamic intracellular organelles with ultrastructural heterogeneity
reflecting the behaviour and functions of the cells. The ultrastructural remodelling, performed …

Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome‐Induced Pyroptosis via Inhibiting the TLR4/NF‐κB/PFKFB3 Signaling in …

Y Zhang, W Liu, Y Zhong, Q Li, M Wu… - Oxidative Medicine …, 2021 - Wiley Online Library
NOD‐like receptor family, pyrin domain‐containing protein 3 (NLRP3) inflammasome‐
mediated pyroptosis is a crucial event in the preeclamptic pathogenesis, tightly linked with …

ADPGK‐AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth

A Karger, S Mansouri, MS Leisegang, A Weigert… - The EMBO …, 2023 - embopress.org
Long noncoding RNAs (lncRNAs) influence the transcription of gene networks in many cell
types, but their role in tumor‐associated macrophages (TAMs) is still largely unknown. We …

[HTML][HTML] Mitochondrial homeostasis regulates definitive endoderm differentiation of human pluripotent stem cells

J Lv, Y Yi, Y Qi, C Yan, W Jin, L Meng, D Zhang… - Cell death …, 2022 - nature.com
Cellular organelles play fundamental roles in almost all cell behaviors. Mitochondria have
been reported to be functionally linked to various biological processes, including …

[HTML][HTML] Role of mitochondrial fission-related genes in mitochondrial morphology and energy metabolism in mouse embryonic stem cells

BJ Seo, J Choi, H La, O Habib, Y Choi, K Hong, JT Do - Redox Biology, 2020 - Elsevier
Mitochondria, the major organelles that produce energy for cell survival and function,
dynamically change their morphology via fusion and fission, a process called mitochondrial …

[HTML][HTML] Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence

Q Luo, H Pui, J Chen, L Yu, PR Jannig, Y Pei, L Zhao… - Cell reports, 2023 - cell.com
Different formative pluripotent stem cells harboring similar functional properties have been
recently established to be lineage neutral and germline competent yet have distinct …

Metabolic characterization of human sperm cells using the Seahorse metabolic flux analyzer

A Freitas‐Martins, MI Sousa, MI Cristo… - …, 2024 - Wiley Online Library
Background The concerning trend on male infertility global prevalence, together with the
unexplainable causes in half of those cases, highlights that there are still aspects of this …

Lactate enhances mouse ES cell differentiation toward XEN cells in vitro

MI Gatie, TT Cooper, R Khazaee, GA Lajoie… - Stem Cells, 2022 - academic.oup.com
Metabolism plays a crucial role for cell survival and function; however, recent evidence has
implicated it in regulating embryonic development. In the embryo, the inner cell mass …

Optoplasmonic Modulation of Cell Metabolic State Promotes Rapid Cell Differentiation

G Qi, C Xu, J Wang, Y Tian, B Wang, Y Zhang… - Analytical …, 2022 - ACS Publications
Cell differentiation plays a vital role in mediating organ formation and tissue repair and
regeneration. Although rapid and effective methods to stimulate cell differentiation for clinical …