Sleep and epilepsy: A snapshot of knowledge and future research lines

L Nobili, B Frauscher, S Eriksson… - Journal of sleep …, 2022 - Wiley Online Library
Sleep and epilepsy have a reciprocal relationship, and have been recognized as bedfellows
since antiquity. However, research on this topic has made a big step forward only in recent …

Augmenting hippocampal–prefrontal neuronal synchrony during sleep enhances memory consolidation in humans

M Geva-Sagiv, EA Mankin, D Eliashiv, S Epstein… - Nature …, 2023 - nature.com
Memory consolidation during sleep is thought to depend on the coordinated interplay
between cortical slow waves, thalamocortical sleep spindles and hippocampal ripples, but …

Bidirectional relationships of sleep and epilepsy in adults with epilepsy

M Grigg-Damberger, N Foldvary-Schaefer - Epilepsy & Behavior, 2021 - Elsevier
This targeted review addresses the best accepted and most intriguing recent observations
on the complex relationships between sleep and epilepsy. Ten to 15% of all epilepsies are …

A subpopulation of spikes predicts successful epilepsy surgery outcome

J Thomas, P Kahane, C Abdallah, T Avigdor… - Annals of …, 2023 - Wiley Online Library
Objective Epileptic spikes are the traditional interictal electroencephalographic (EEG)
biomarker for epilepsy. Given their low specificity for identifying the epileptogenic zone (EZ) …

[HTML][HTML] Robust chronic convulsive seizures, high frequency oscillations, and human seizure onset patterns in an intrahippocampal kainic acid model in mice

CP Lisgaras, HE Scharfman - Neurobiology of disease, 2022 - Elsevier
Intrahippocampal kainic acid (IHKA) has been widely implemented to simulate temporal
lobe epilepsy (TLE), but evidence of robust seizures is usually limited. To resolve this …

Spike patterns surrounding sleep and seizures localize the seizure‐onset zone in focal epilepsy

EC Conrad, AY Revell, AS Greenblatt, RS Gallagher… - …, 2023 - Wiley Online Library
Objective Interictal spikes help localize seizure generators as part of surgical planning for
drug‐resistant epilepsy. However, there are often multiple spike populations whose …

SleepSEEG: automatic sleep scoring using intracranial EEG recordings only

N von Ellenrieder, L Peter-Derex… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. To perform automatic sleep scoring based only on intracranial
electroencephalography (iEEG), without the need for scalp EEG), electrooculography (EOG) …

Correcting for physiological ripples improves epileptic focus identification and outcome prediction

WJEM Zweiphenning, N von Ellenrieder, F Dubeau… - …, 2022 - Wiley Online Library
Objective The integration of high‐frequency oscillations (HFOs; ripples [80–250 Hz], fast
ripples [250–500 Hz]) in epilepsy evaluation is hampered by physiological HFOs, which …

The differing effects of sleep on ictal and interictal network dynamics in drug‐resistant epilepsy

S Hannan, J Thomas, K Jaber, C El Kosseifi… - Annals of …, 2024 - Wiley Online Library
Objective Sleep has important influences on focal interictal epileptiform discharges (IEDs),
and the rates and spatial extent of IEDs are increased in non‐rapid eye movement (NREM) …

Accuracy of high-frequency oscillations recorded intraoperatively for classification of epileptogenic regions

SA Weiss, RJ Staba, A Sharan, C Wu, D Rubinstein… - Scientific reports, 2021 - nature.com
To see whether acute intraoperative recordings using stereo EEG (SEEG) electrodes can
replace prolonged interictal intracranial EEG (iEEG) recording, making the process more …