Exploring ncRNA-mediated regulation of EGFR signalling in glioblastoma: From mechanisms to therapeutics
Glioblastoma (GBM) is the most prevalent and deadly primary brain tumor type, with a
discouragingly low survival rate and few effective treatments. An important function of the …
discouragingly low survival rate and few effective treatments. An important function of the …
Hypoxia-inducible factor 1alpha and vascular endothelial growth factor in Glioblastoma Multiforme: a systematic review going beyond pathologic implications
Glioblastoma multiforme (GBM) is an aggressive primary brain tumor characterized by
extensive heterogeneity and vascular proliferation. Hypoxic conditions in the tissue …
extensive heterogeneity and vascular proliferation. Hypoxic conditions in the tissue …
Comprehensive analysis reveals epithelial growth factor receptor as a potential diagnostic biomarker in glioblastoma multiforme
Glioblastoma multiforme (GBM), a highly aggressive tumor of the central nervous system, is
the most common malignant brain tumor and poses a significant risk to life. GBM patients …
the most common malignant brain tumor and poses a significant risk to life. GBM patients …
[HTML][HTML] Predictive and Prognostic Significance of Molecular Biomarkers in Glioblastoma
S Shah, A Nag, SV Sachithanandam, B Lucke-Wold - Biomedicines, 2024 - mdpi.com
Glioblastoma multiforme (GBM), a WHO grade 4 glioma, is the most common and
aggressive primary brain tumor, characterized by rapid progression and poor prognosis. The …
aggressive primary brain tumor, characterized by rapid progression and poor prognosis. The …
PAQR4 oncogene: a novel target for cancer therapy
Despite decades of basic and clinical research and trials of promising new therapies, cancer
remains a major cause of morbidity and mortality due to the emergence of drug resistance to …
remains a major cause of morbidity and mortality due to the emergence of drug resistance to …
Chitosan Functionalized Skin-Adhesive Formulation for Ergotamine Delivery in Melanoma Treatment
This study develops a skin-penetrating drug delivery system of thiolated chitosan-lithocholic
acid nanomicelles for the treatment of melanoma. In this regard, ergotamine was selected as …
acid nanomicelles for the treatment of melanoma. In this regard, ergotamine was selected as …
[HTML][HTML] Complex Diagnostic Challenges in Glioblastoma: The Role of 18F-FDOPA PET Imaging
Glioblastoma multiforme (GBM) remains one of the most aggressive and lethal forms of brain
cancer, characterized by rapid proliferation and diffuse infiltration into the surrounding brain …
cancer, characterized by rapid proliferation and diffuse infiltration into the surrounding brain …
[HTML][HTML] Mesenchymal-Type Genetic Mutations Are Likely Prerequisite for Glioblastoma Multiforme to Metastasize Outside the Central Nervous System: An Original …
BJ Laurin, R Treffy, JM Connelly, M Straza… - World Neurosurgery, 2024 - Elsevier
Background Glioblastoma multiforme (GBM) is the most aggressive and prevalent type of
malignant brain tumor, yet it metastasizes outside the central nervous system (CNS) in 0.4 …
malignant brain tumor, yet it metastasizes outside the central nervous system (CNS) in 0.4 …
Preliminary Analysis of Solute Carrier Family in Nucleotide Rescue Synthesis in Glioma
Y Chen, Q Sun, Z Li - Journal of Craniofacial Surgery, 2024 - journals.lww.com
Glioma is a highly proliferative and aggressive tumor type that arises from glial cells in the
central nervous system. The nucleotides required for the proliferation and replication of …
central nervous system. The nucleotides required for the proliferation and replication of …
Unraveling the Role of Transcription Factor SP1 and H3K9 Acetylation in MGMT Regulation and Temozolomide Resistance in Glioblastoma Multiforme
L Gu, Y Wang, H Xing, P Hu, Y Wang, W Ma - 2023 - researchsquare.com
Glioblastoma multiforme (GBM) is recognized as a highly aggressive brain tumor, exhibiting
profound resistance to temozolomide (TMZ) chemotherapy. While methylation of the MGMT …
profound resistance to temozolomide (TMZ) chemotherapy. While methylation of the MGMT …