Fifty years have passed since the discovery of glial fibrillary acidic protein (GFAP) by
Lawrence Eng and colleagues. Now recognized as a member of the intermediate filament …

Gliomas are a heterogenous group of malignant primary brain tumors that arise from glia
cells or their progenitors and rely on accurate diagnosis for prognosis and treatment …

Human aldo-keto reductase family 1 member C3 (AKR1C3) is known as a hormone activity
regulator and prostaglandin F (PGF) synthase that regulates the occupancy of hormone …

Glioma is the most common form of malignant primary brain tumours in adults. Their highly
invasive nature makes the disease incurable to date, emphasizing the importance of better …

Glial fibrillary acidic protein (GFAP) is an intermediate filament protein that is characteristic
for astrocytes and neural stem cells, and their malignant analogues in glioma. Since the …

Tunneling nanotubes (TNTs) are long F-actin-positive plasma membrane bridges
connecting distant cells, allowing the intercellular transfer of cellular cargoes, and are found …

Introduction Liquid biopsies are promising diagnostic tools for glioma. In this quantitative
systematic review, we investigate whether the detection of intermediate filaments (IF) in body …

Intermediate filaments are a fundamental component of the cytoskeleton in neurons and
astrocytes. The main intermediate filament in astrocytes is glial fibrillary acid protein (GFAP) …

Background The expression of aquaporin 4 (AQP4) and intermediate filament (IF) proteins is
altered in malignant glioblastoma (GBM), yet the expression of the major IF-based cytolinker …

Astrocytes, the most abundant glial cells in the central nervous system (CNS), have
numerous integral roles in all CNS functions. They are essential for synaptic transmission …