Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases

A El Midaoui, I Ghzaiel, D Vervandier-Fasseur, M Ksila… - Nutrients, 2022 - mdpi.com
Saffron (Crocus sativus L.) is a medicinal plant, originally cultivated in the East and Middle
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …

Carotenoids, inflammation, and oxidative stress—implications of cellular signaling pathways and relation to chronic disease prevention

A Kaulmann, T Bohn - Nutrition research, 2014 - Elsevier
Several epidemiologic studies have shown that diets rich in fruits and vegetables reduce the
risk of developing several chronic diseases, such as type 2 diabetes, atherosclerosis, and …

[HTML][HTML] A comprehensive review of the pharmacological potential of Crocus sativus and its bioactive apocarotenoids

SI Bukhari, M Manzoor, MK Dhar - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Crocus sativus is an herbaceous plant that belongs to family Iridaceae. It is commonly
known as saffron and has been used for medicinal purposes since many centuries in India …

[HTML][HTML] Immunoregulatory and anti-inflammatory properties of Crocus sativus (Saffron) and its main active constituents: A review

M Zeinali, MR Zirak, SA Rezaee, G Karimi… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
The medicinal uses of saffron, the dried stigmas of Crocus sativus L., have very long history
in food coloring agent, and flavoring agent as well as traditional medicine for the treatment of …

Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action

AL Lopresti, PD Drummond - … : Clinical and Experimental, 2014 - Wiley Online Library
Background Saffron, a spice derived from the flower of Crocus sativus, has now undergone
several trials examining its antidepressant effects and, in a recent meta‐analysis, was …

Saffron in the treatment of depression, anxiety and other mental disorders: Current evidence and potential mechanisms of action

M Shafiee, S Arekhi, A Omranzadeh… - Journal of Affective …, 2018 - Elsevier
Background Depression and anxiety are two common mental health problems with high
economic and social costs. Currently, a number of treatments are available for patients with …

Crocin: A fighter against inflammation and pain

M Hashemzaei, C Mamoulakis, K Tsarouhas… - Food and Chemical …, 2020 - Elsevier
Crocin, a water-soluble carotenoid, is known as a pharmacologically active compound,
particularly for its potent anti-oxidant activity. The present work provides a comprehensive …

Saffron extract and crocin exert anti-inflammatory and anti-oxidative effects in a repetitive mild traumatic brain injury mouse model

M Salem, M Shaheen, A Tabbara, J Borjac - Scientific Reports, 2022 - nature.com
Abstract Saffron Crocus sativus L.(C. sativus) is a flower from the iridaceous family. Crocin,
saffron's major constituent, and saffron have anti-oxidative and anti-inflammatory activities …

Antiinflammatory, Antioxidant, and Immunomodulatory Effects of Crocus sativus L. and its Main Constituents

MH Boskabady, T Farkhondeh - Phytotherapy Research, 2016 - Wiley Online Library
Crocus sativus L.(C. sativus), commonly known as saffron, is used as a food additive,
preservative, and medicinal herb. Traditionally, it has been used as an alternative treatment …

Fabrication and characterization of 3D printing biocompatible crocin-loaded chitosan/collagen/hydroxyapatite-based scaffolds for bone tissue engineering …

N Jirofti, M Hashemi, A Moradi, F Kalalinia - International Journal of …, 2023 - Elsevier
Abstract Introduction Crocin (Cro) is a bioactive biomaterial with properties that promote
osteoconduction, osteoinduction, and osteogenic differentiation, making it an ideal …