[PDF][PDF] Natural plant resource flavonoids as potential therapeutic drugs for pulmonary fibrosis

MC Wang - Heliyon, 2023 - cell.com
Pulmonary fibrosis is an enduring and advancing pulmonary interstitial disease caused by
multiple factors that ultimately lead to structural changes in normal lung tissue. Currently …

Natural compounds target programmed cell death (PCD) signaling mechanism to treat ulcerative colitis: a review

B Chen, X Dong, JL Zhang, X Sun, L Zhou… - Frontiers in …, 2024 - frontiersin.org
Ulcerative colitis (UC) is a nonspecific inflammatory bowel disease characterized by
abdominal pain, bloody diarrhea, weight loss, and colon shortening. However, UC is difficult …

Hepatoprotective effect of alpinetin on thioacetamide-induced liver fibrosis in sprague dawley rat

SH Shareef, ASM Juma, DNF Agha, AR Alzahrani… - Applied Sciences, 2023 - mdpi.com
Alpinetin is an original medicinal plant flavonoid derived from Alpinia katsumadai and has
several biological activities. The current research aimed to evaluate the hepatoprotective …

[HTML][HTML] Identification of antidiabetic constituents in Polygonatum odoratum (Mill.) Druce by UPLC-Orbitrap-MS, network pharmacology and molecular docking

QH Liu, JQ Li, JW Tang, YD Zhang, MY Zhou… - Arabian Journal of …, 2023 - Elsevier
Polygonatum odoratum has been known as having therapeutic effects on diabetes.
However, due to its complex composition, it is difficult to elucidate the molecular …

Flavonoid synthesis in Lamiophlomis rotata from Qinghai-Tibet Plateau is influenced by soil properties, microbial community, and gene expression

F Qiao, Y Lu, G Geng, L Zhou, Z Chen, L Wang… - Journal of Plant …, 2023 - Elsevier
Lamiophlomis rotata is a medicinal plant in Qinghai-Tibet Plateau, in which flavonoid
compounds are the major medicinal components. However, it remains unclear how …

Theabrownin: a dietary nutraceutical with diverse anticancer mechanisms

MF Maqbool, S Gul, M Ishaq, A Maryam… - Natural Product …, 2024 - Taylor & Francis
Cancer, a highly deadly disease, necessitates safe, cost-effective, and readily accessible
treatments to mitigate its impact. Theabrownin (THBR), a polyphenolic pigment found in Pu …

Discovery of Potential Natural STAT3 Inhibitors: An in silico Molecular Docking and Molecular Dynamics Study

S Gul, S Muhammad, M Irfan… - Journal of …, 2024 - ui.adsabs.harvard.edu
Cancer is a mechanistically complex and diverse disease with a plethora of fundamental
genetic and epigenetic factors. Signal transducer and activator of transcription-3 (STAT3) is …

Tribulus terrestris Cytotoxicity against Breast Cancer MCF-7 and Lung Cancer A549 Cell Lines Is Mediated via Activation of Apoptosis, Caspase-3, DNA Degradation …

AM Alshabi, SA Alkahtani, IA Shaikh, MAA Orabi… - Separations, 2022 - mdpi.com
The primary objective of this research was to use flow cytometry to gain mechanistic insights
into the cytotoxic effects of Tribulus terrestris extracts on breast cancer (MCF7) and lung …

Network analysis and basic experiments on the inhibition of renal cancer proliferation and migration by alpinetin through PI3K/AKT/mTOR pathway

Y Guo, L Jiang, S Luo, D Hu, X Zhao… - Current Molecular …, 2024 - ingentaconnect.com
Background: Alpinetin, a natural flavonoid, has been shown to have anticancer effects on
many tumors. This study investigated the antitumor effect of alpinetin on renal clear cell …