Effects of chronic fluoxetine treatment on anxiety-and depressive-like behaviors in adolescent rodents–systematic review and meta-analysis
J Kryst, I Majcher-Maślanka, A Chocyk - Pharmacological Reports, 2022 - Springer
Background Drugs prescribed for psychiatric disorders in adolescence should be studied
very extensively since they can affect developing and thus highly plastic brain differently …
very extensively since they can affect developing and thus highly plastic brain differently …
Boosting neurogenesis in the adult hippocampus using antidepressants and mesenchymal stem cells
M Kot, PK Neglur, A Pietraszewska, L Buzanska - Cells, 2022 - mdpi.com
The hippocampus is one of the few privileged regions (neural stem cell niche) of the brain,
where neural stem cells differentiate into new neurons throughout adulthood. However …
where neural stem cells differentiate into new neurons throughout adulthood. However …
Long-term overconsumption of sugar starting at adolescence produces persistent hyperactivity and neurocognitive deficits in adulthood
Sugar has become embedded in modern food and beverages. This has led to
overconsumption of sugar in children, adolescents, and adults, with more than 60 countries …
overconsumption of sugar in children, adolescents, and adults, with more than 60 countries …
Effects of adolescent administration of fluoxetine on novel object recognition memory, anxiety-like behaviors, and hippocampal brain-derived neurotrophic factor level
F Sadegzadeh, N Sakhaie, R Dehghany, O Adak… - Life sciences, 2020 - Elsevier
Aims Fluoxetine (FLX) is a common selective serotonin reuptake inhibitor, which is used in
adolescents with psychiatric disorders. Controversial results have been obtained in different …
adolescents with psychiatric disorders. Controversial results have been obtained in different …
Enduring effects of adolescent ketamine exposure on cocaine-and sucrose-induced reward in male and female C57BL/6 mice
I Garcia-Carachure, FJ Flores-Ramirez… - …, 2020 - nature.com
Ketamine has shown promising antidepressant efficacy for adolescent treatment-resistant
depression. However, the potential enduring consequences of ketamine exposure have not …
depression. However, the potential enduring consequences of ketamine exposure have not …
Chronic social defeat stress in prairie voles (Microtus ochrogaster): A preclinical model for the study of depression-related phenotypes
M Rodriguez, A Themann, I Garcia-Carachure… - Journal of Affective …, 2024 - Elsevier
Background Stress-induced illnesses, like major depression, are among the leading causes
of disability across the world. Consequently, there is a dire need for the validation of …
of disability across the world. Consequently, there is a dire need for the validation of …
[HTML][HTML] Sex-Specific Alterations in Spatial Memory and Hippocampal AKT-mTOR Signaling in Adult Mice Pre-exposed to Ketamine and/or Psychological Stress …
Background Ketamine (KET) is administered to manage major depression in adolescent
patients. However, the long-term effects of juvenile KET exposure on memory-related tasks …
patients. However, the long-term effects of juvenile KET exposure on memory-related tasks …
Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood
FJ Flores-Ramirez, A Themann, JA Sierra-Fonseca… - Scientific reports, 2021 - nature.com
The objective of this study was to evaluate whether juvenile fluoxetine (FLX) exposure
induces long-term changes in baseline responses to anxiety-inducing environments, and if …
induces long-term changes in baseline responses to anxiety-inducing environments, and if …
Adolescent fluoxetine exposure induces persistent gene expression changes in the hippocampus of adult male C57BL/6 mice
SD Iñiguez, FJ Flores-Ramirez, A Themann… - Molecular neurobiology, 2021 - Springer
Mood-related disorders have a high prevalence among children and adolescents, posing a
public health challenge, given their adverse impact on these young populations. Treatment …
public health challenge, given their adverse impact on these young populations. Treatment …
Early-life ketamine exposure attenuates the preference for ethanol in adolescent Sprague-Dawley rats
Ketamine, a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, produces
quick and effective antidepressant results in depressed juvenile and adult individuals. The …
quick and effective antidepressant results in depressed juvenile and adult individuals. The …