Fiber-type shifting in sarcopenia of old age: proteomic profiling of the contractile apparatus of skeletal muscles

P Dowling, S Gargan, D Swandulla… - International Journal of …, 2023 - mdpi.com
The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Pathogenesis, intervention, and current status of drug development for sarcopenia: a review

JY Jang, D Kim, ND Kim - Biomedicines, 2023 - mdpi.com
Sarcopenia refers to the loss of muscle strength and mass in older individuals and is a major
determinant of fall risk and impaired ability to perform activities of daily living, often leading …

[HTML][HTML] Therapeutic application of natural compounds for skeletal muscle-associated metabolic disorders: A review on diabetes perspective

K Ahmad, S Shaikh, JH Lim, SS Ahmad… - Biomedicine & …, 2023 - Elsevier
Skeletal muscle (SM) plays a vital role in energy and glucose metabolism by regulating
insulin sensitivity, glucose uptake, and blood glucose homeostasis. Impaired SM …

[HTML][HTML] The roles of growth factors and hormones in the regulation of muscle satellite cells for cultured meat production

SS Ahmad, HJ Chun, K Ahmad, S Shaikh… - Journal of Animal …, 2023 - ncbi.nlm.nih.gov
Cultured meat is a potential sustainable food generated by the in vitro myogenesis of muscle
satellite (stem) cells (MSCs). The self-renewal and differentiation properties of MSCs are of …

Sarcopenia and diabetes: A detrimental liaison of advancing age

G Lisco, OE Disoteo, A De Tullio, V De Geronimo… - Nutrients, 2023 - mdpi.com
Sarcopenia is an age-related clinical complaint characterized by the progressive
deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is …

Sarcopenic obesity: involvement of oxidative stress and beneficial role of antioxidant flavonoids

UJ Jung - Antioxidants, 2023 - mdpi.com
Sarcopenic obesity, which refers to concurrent sarcopenia and obesity, is characterized by
decreased muscle mass, strength, and performance along with abnormally excessive fat …

Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

E Espino-Gonzalez, E Dalbram, R Mounier, J Gondin… - Cell Metabolism, 2024 - cell.com
Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …

Therapeutic applications of ginseng natural compounds for health management

SS Ahmad, K Ahmad, YC Hwang, EJ Lee… - International Journal of …, 2023 - mdpi.com
Ginseng is usually consumed as a daily food supplement to improve health and has been
shown to benefit skeletal muscle, improve glucose metabolism, and ameliorate muscle …

Effects of functional training with blood occlusion on the irisin, follistatin, and myostatin myokines in elderly men

F Pazokian, S Amani-Shalamzari, H Rajabi - European Review of Aging …, 2022 - Springer
Background This study aimed to determine the efficacy of functional training with and without
blood flow restriction (BFR) on muscle hypertrophy indices and strength in older men …

Sarcopenia predicts short‐term treatment‐related toxicity in patients undergoing curative‐intent therapy for head and neck cancer: A systematic review and meta …

MA Mascarella, J Ferdus, V Vendra, S Sridharan… - Head & …, 2024 - Wiley Online Library
Sarcopenia is an increasingly recognized biomarker associated with poorer outcomes. The
objective of this study was to ascertain the effect of sarcopenia on treatment tolerance and …