Glial responses to implanted electrodes in the brain

JW Salatino, KA Ludwig, TDY Kozai… - Nature biomedical …, 2017 - nature.com
The use of implants that can electrically stimulate or record electrophysiological or
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …

Chronically implanted intracranial electrodes: tissue reaction and electrical changes

A Campbell, C Wu - Micromachines, 2018 - mdpi.com
The brain-electrode interface is arguably one of the most important areas of study in
neuroscience today. A stronger foundation in this topic will allow us to probe the architecture …

Low-threshold, high-resolution, chronically stable intracortical microstimulation by ultraflexible electrodes

R Lycke, R Kim, P Zolotavin, J Montes, Y Sun… - Cell reports, 2023 - cell.com
Intracortical microstimulation (ICMS) enables applications ranging from neuroprosthetics to
causal circuit manipulations. However, the resolution, efficacy, and chronic stability of …

Chronic in vivo stability assessment of carbon fiber microelectrode arrays

PR Patel, H Zhang, MT Robbins, JB Nofar… - Journal of neural …, 2016 - iopscience.iop.org
Objective. Individual carbon fiber microelectrodes can record unit activity in both acute and
semi-chronic (∼ 1 month) implants. Additionally, new methods have been developed to …

In vivo spatiotemporal dynamics of astrocyte reactivity following neural electrode implantation

SP Savya, F Li, S Lam, SM Wellman, KC Stieger… - Biomaterials, 2022 - Elsevier
Brain computer interfaces (BCIs), including penetrating microelectrode arrays, enable both
recording and stimulation of neural cells. However, device implantation inevitably causes …

Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: new emphasis on the biological interface

NJ Michelson, AL Vazquez, JR Eles… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Implantable neural electrode devices are important tools for neuroscience
research and have an increasing range of clinical applications. However, the intricacies of …

Ultra-small carbon fiber electrode recording site optimization and improved in vivo chronic recording yield

EJ Welle, PR Patel, JE Woods… - Journal of neural …, 2020 - iopscience.iop.org
Objective. Carbon fiber electrodes may enable better long-term brain implants, minimizing
the tissue response commonly seen with silicon-based electrodes. The small diameter fiber …

[HTML][HTML] The effect of a Mn (III) tetrakis (4-benzoic acid) porphyrin (MnTBAP) coating on the chronic recording performance of planar silicon intracortical microelectrode …

AG Hernandez-Reynoso, BS Sturgill, GF Hoeferlin… - Biomaterials, 2023 - Elsevier
Intracortical microelectrode arrays (MEAs) are used to record neural activity. However, their
implantation initiates a neuroinflammatory cascade, involving the accumulation of reactive …

Unique electrophysiological and impedance signatures between encapsulation types: An analysis of biological Utah array failure and benefit of a biomimetic coating …

PA Cody, JR Eles, CF Lagenaur, TDY Kozai, XT Cui - Biomaterials, 2018 - Elsevier
Intracortical microelectrode arrays, especially the Utah array, remain the most common
choice for obtaining high dimensional recordings of spiking neural activity for brain computer …

Electrodeposited platinum-iridium coating improves in vivo recording performance of chronically implanted microelectrode arrays

IR Cassar, C Yu, J Sambangi, CD Lee, JJ Whalen III… - Biomaterials, 2019 - Elsevier
Reliable single unit neuron recordings from chronically implanted microelectrode arrays
(MEAs) are essential tools in the field of neural engineering. However, following …