[HTML][HTML] Pharmaceutical and nutraceutical potential of natural bioactive pigment: astaxanthin
Abstract Astaxanthin (3, 3′-dihydroxy-β, β-carotene-4, 4′-dione) is an orange-red,
lipophilic keto-carotenoid pigment. It is majorly found in marine ecosystems particularly in …
lipophilic keto-carotenoid pigment. It is majorly found in marine ecosystems particularly in …
[HTML][HTML] Parkinson's disease risk and hyperhomocysteinemia: the possible link
HM Al-Kuraishy, AI Al-Gareeb, YHA Elewa… - Cellular and Molecular …, 2023 - Springer
Parkinson's disease (PD) is one of the most common degenerative brain disorders caused
by the loss of dopaminergic neurons in the substantia nigra (SN). Lewy bodies and …
by the loss of dopaminergic neurons in the substantia nigra (SN). Lewy bodies and …
[HTML][HTML] Mitochondria in neuroprotection by phytochemicals: Bioactive polyphenols modulate mitochondrial apoptosis system, function and structure
M Naoi, Y Wu, M Shamoto-Nagai… - International journal of …, 2019 - mdpi.com
In aging and neurodegenerative diseases, loss of distinct type of neurons characterizes
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …
[HTML][HTML] The neuroprotective effects of astaxanthin: therapeutic targets and clinical perspective
S Fakhri, I Yosifova Aneva, MH Farzaei… - Molecules, 2019 - mdpi.com
As the leading causes of human disability and mortality, neurological diseases affect
millions of people worldwide and are on the rise. Although the general roles of several …
millions of people worldwide and are on the rise. Although the general roles of several …
Astaxanthin targets PI3K/Akt signaling pathway toward potential therapeutic applications
The complex pathophysiological mechanisms behind destructive chronic conditions,
including cancer, neurodegenerative diseases, diabetes mellitus, cardiovascular diseases …
including cancer, neurodegenerative diseases, diabetes mellitus, cardiovascular diseases …
[HTML][HTML] Anti-apoptotic effects of carotenoids in neurodegeneration
HA Park, MM Hayden, S Bannerman, J Jansen… - Molecules, 2020 - mdpi.com
Apoptosis, programmed cell death type I, is a critical part of neurodegeneration in cerebral
ischemia, Parkinson's, and Alzheimer's disease. Apoptosis begins with activation of pro …
ischemia, Parkinson's, and Alzheimer's disease. Apoptosis begins with activation of pro …
[HTML][HTML] Molecular mechanisms of astaxanthin as a potential neurotherapeutic agent
Neurological disorders are diseases of the central and peripheral nervous system that affect
millions of people, and the numbers are rising gradually. In the pathogenesis of …
millions of people, and the numbers are rising gradually. In the pathogenesis of …
[HTML][HTML] Targeting mitochondrial dysfunction in neurodegenerative diseases: expanding the therapeutic approaches by plant-derived natural products
X Zhang, L Wang, B Li, J Shi, J Xu, M Yuan - Pharmaceuticals, 2023 - mdpi.com
Mitochondria are the primary source of energy production in neurons, supporting the high
energy consumption of the nervous system. Inefficient and dysfunctional mitochondria in the …
energy consumption of the nervous system. Inefficient and dysfunctional mitochondria in the …
[HTML][HTML] The role of dietary antioxidants in the pathogenesis of neurodegenerative diseases and their impact on cerebral oxidoreductive balance
A Winiarska-Mieczan, E Baranowska-Wójcik… - Nutrients, 2020 - mdpi.com
Neurodegenerative diseases are progressive diseases of the nervous system that lead to
neuron loss or functional disorders. Neurodegenerative diseases require long-term …
neuron loss or functional disorders. Neurodegenerative diseases require long-term …
Astaxanthin suppresses endoplasmic reticulum stress and protects against neuron damage in Parkinson's disease by regulating miR-7/SNCA axis
DF Shen, HP Qi, C Ma, MX Chang, WN Zhang… - Neuroscience …, 2021 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative disorder that featured by the loss
of dopaminergic neurons. Astaxanthin (AST), an important antioxidant, is demonstrated to be …
of dopaminergic neurons. Astaxanthin (AST), an important antioxidant, is demonstrated to be …