Virulence Factors of Candida spp. and Host Immune Response Important in the Pathogenesis of Vulvovaginal Candidiasis

P Czechowicz, J Nowicka, G Gościniak - International journal of molecular …, 2022 - mdpi.com
Vulvovaginal candidiasis (VVC) is one of the most common types of vaginal infections in
women around the world and is often underestimated by both patients and doctors …

What Do We Know about Candida auris? State of the Art, Knowledge Gaps, and Future Directions

V Garcia-Bustos, MD Cabanero-Navalon, A Ruiz-Saurí… - Microorganisms, 2021 - mdpi.com
Candida auris has unprecedently emerged as a multidrug resistant fungal pathogen,
considered a serious global threat due to its potential to cause nosocomial outbreaks and …

Mechanisms of pathogenicity for the emerging fungus Candida auris

MV Horton, AM Holt, JE Nett - Plos Pathogens, 2023 - journals.plos.org
Candida auris recently emerged as an urgent public health threat, causing outbreaks of
invasive infections in healthcare settings throughout the world. This fungal pathogen persists …

The many faces of Candida auris: Phenotypic and strain variation in an emerging pathogen

DJ Santana, G Zhao, TR O'Meara - Plos Pathogens, 2024 - journals.plos.org
Candida auris is an emerging fungal pathogen with unusual evolutionary history—there are
multiple distinct phylogeographic clades showing a near simultaneous transition from a …

Overview about Candida auris: what's up 12 years after its first description?

G Desoubeaux, AT Coste, C Imbert… - Journal of Medical …, 2022 - Elsevier
Candida auris has been described as an emerging yeast species during the last decade. As
many as 25% of its strains may naturally exhibit multi-drug resistance to the currently …

Antifungal Activity of the Phenolic Compounds Ellagic Acid (EA) and Caffeic Acid Phenethyl Ester (CAPE) against Drug-Resistant Candida auris

FC Possamai Rossatto, N Tharmalingam, IE Escobar… - Journal of Fungi, 2021 - mdpi.com
Candida auris is an emerging healthcare-associated fungal pathogen that has become a
serious global health threat. Current treatment options are limited due to drug resistance …

Candida auris undergoes adhesin-dependent and -independent cellular aggregation

C Pelletier, S Shaw, S Alsayegh, AJP Brown… - PLoS …, 2024 - journals.plos.org
Candida auris is a fungal pathogen of humans responsible for nosocomial infections with
high mortality rates. High levels of resistance to antifungal drugs and environmental …

Galleria mellonella immune melanization is fungicidal during infection

DFQ Smith, Q Dragotakes, M Kulkarni… - Communications …, 2022 - nature.com
A key component of the insect immune response is melanin production, including within
nodules, or aggregations of immune cells surrounding microbes. Melanization produces …

Galleria mellonella for systemic assessment of anti-Candida auris using amphotericin B loaded in nanoemulsion

GD Marena, MADS Ramos, LC Lima, M Chorilli… - Science of The Total …, 2022 - Elsevier
Galleria mellonella is a model that uses adult larvae to assess the prophylactic, therapeutic,
and acute toxic potential of substances. Given their benefits, G. mellonella models are being …

Amphotericin B-loaded natural latex dressing for treating Candida albicans wound infections using Galleria mellonella model

RD Herculano, CE Dos Reis, SMB de Souza… - Journal of Controlled …, 2024 - Elsevier
Amphotericin B (AmB) is the gold standard for antifungal drugs. However, AmB systemic
administration is restricted because of its side effects. Here, we report AmB loaded in natural …