Tumor immune microenvironment in head and neck cancers
SMY Chen, AL Krinsky, RA Woolaver… - Molecular …, 2020 - Wiley Online Library
Head and neck cancers are a heterogeneous group of tumors that are highly aggressive
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …
Recent updates in cancer immunotherapy: a comprehensive review and perspective of the 2018 China Cancer Immunotherapy Workshop in Beijing
Z Li, W Song, M Rubinstein, D Liu - Journal of hematology & oncology, 2018 - Springer
The immune system is the hard-wired host defense mechanism against pathogens as well
as cancer. Five years ago, we pondered the question if the era of cancer immunotherapy …
as cancer. Five years ago, we pondered the question if the era of cancer immunotherapy …
Natural killer cell-related prognosis signature characterizes immune landscape and predicts prognosis of HNSCC
H Chi, X Xie, Y Yan, G Peng, DF Strohmer… - Frontiers in …, 2022 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC), the most common head
and neck cancer, is highly aggressive and heterogeneous, resulting in variable prognoses …
and neck cancer, is highly aggressive and heterogeneous, resulting in variable prognoses …
[HTML][HTML] The association of PD-L1 expression with the efficacy of anti-PD-1/PD-L1 immunotherapy and survival of non-small cell lung cancer patients: a meta-analysis …
Y Xu, B Wan, X Chen, P Zhan, Y Zhao… - Translational Lung …, 2019 - ncbi.nlm.nih.gov
Background We conducted a meta-analysis to evaluate the efficacy of anti-programmed cell
death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) monotherapy or immunotherapy …
death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) monotherapy or immunotherapy …
[HTML][HTML] Response to salvage chemotherapy after progression on immune checkpoint inhibitors in patients with recurrent and/or metastatic squamous cell carcinoma …
K Saleh, A Daste, N Martin, E Pons-Tostivint… - European Journal of …, 2019 - Elsevier
Background Immune checkpoint inhibitors (ICI) are active in patients with
recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). Recent …
recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). Recent …
[HTML][HTML] c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation
YC Tang, JR Hsiao, SS Jiang, JY Chang, PY Chu… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: NRF2, a redox sensitive transcription factor, is up-regulated in head and neck
squamous cell carcinoma (HNSCC), however, the associated impact and regulatory …
squamous cell carcinoma (HNSCC), however, the associated impact and regulatory …
HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis
C Pan, N Issaeva, WG Yarbrough - Cancers of the head & neck, 2018 - Springer
Understanding of oropharyngeal squamous cell carcinoma has significantly progressed
over the last decades, and the concept that this disease can be subdivided into two distinct …
over the last decades, and the concept that this disease can be subdivided into two distinct …
Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma
Y Qin, X Zheng, W Gao, B Wang, Y Wu - Molecular Therapy-Oncolytics, 2021 - cell.com
Head and neck squamous cell carcinomas (HNSCCs) are a type of common malignant
tumor, mainly manifesting as oropharyngeal, oral cavity, laryngopharyngeal …
tumor, mainly manifesting as oropharyngeal, oral cavity, laryngopharyngeal …
Cytokines, chemokines, and other biomarkers of response for checkpoint inhibitor therapy in skin cancer
Immunotherapy for skin malignancies has ushered in a new era for cancer treatments by
demonstrating unprecedented durable responses in the setting of metastatic Melanoma …
demonstrating unprecedented durable responses in the setting of metastatic Melanoma …
The reversal of immune exclusion mediated by tadalafil and an anti-tumor vaccine also induces PDL1 upregulation in recurrent head and neck squamous cell …
Myeloid Derived suppressor cells (MDSCs) play a key role in the progression and
recurrence of human malignancies and in restraining the efficacy of adjuvant therapies. We …
recurrence of human malignancies and in restraining the efficacy of adjuvant therapies. We …