Opportunities and alternatives of modern radiation oncology and surgery for the management of resectable brain metastases

CD Diehl, FA Giordano, AL Grosu, S Ille, KH Kahl… - Cancers, 2023 - mdpi.com
Simple Summary Brain metastases are of increasing concern in the management of cancer
patients. New systemic treatment options like specific targeting agents or immune …

Current status and recent advances in resection cavity irradiation of brain metastases

G Minniti, M Niyazi, N Andratschke, M Guckenberger… - Radiation …, 2021 - Springer
Despite complete surgical resection brain metastases are at significant risk of local
recurrence without additional radiation therapy. Traditionally, the addition of postoperative …

Predictors of leptomeningeal disease following hypofractionated stereotactic radiotherapy for intact and resected brain metastases

TK Nguyen, A Sahgal, J Detsky, EG Atenafu… - Neuro …, 2020 - academic.oup.com
Background The objective was to evaluate the risk and predictors of developing
leptomeningeal disease (LMD) in patients with brain metastases treated with 5-fraction …

Inter-fraction dynamics during post-operative 5 fraction cavity hypofractionated stereotactic radiotherapy with a MR LINAC: a prospective serial imaging study

H Tan, J Stewart, M Ruschin, MH Wang… - Journal of Neuro …, 2022 - Springer
Abstract Purpose/Objective (s) This study examined changes in the clinical target volume
(CTV) and associated clinical implications on a magnetic resonance imaging linear …

Neoadjuvant stereotactic radiosurgery: a further evolution in the management of brain metastases

C Udovicich, C Phillips, DL Kok, D Tange… - Current Oncology …, 2019 - Springer
Abstract Purpose of Review Recent randomized evidence has supported the use of
resection followed by stereotactic radiosurgery (SRS) as standard of care for patients with a …

Optimal timing of radiotherapy following brain metastases surgery

NK Yaghi, S Radu, JG Nugent… - Neuro-oncology …, 2022 - academic.oup.com
Background There is growing evidence supporting the need for a short time delay before
starting radiotherapy (RT) treatment postsurgery for most optimal responses. The timing of …

What if: A retrospective reconstruction of resection cavity stereotactic radiosurgery to mimic neoadjuvant stereotactic radiosurgery

G Acker, M Nachbar, N Soffried, B Bodnar… - Frontiers in …, 2023 - frontiersin.org
Introduction Neoadjuvant stereotactic radiosurgery (NaSRS) of brain metastases has gained
importance, but it is not routinely performed. While awaiting the results of prospective …

[HTML][HTML] Dosimetric feasibility of direct post-operative MR-Linac-based stereotactic radiosurgery for resection cavities of brain metastases

E Seravalli, M Sierts, E Brand, M Maspero… - Radiotherapy and …, 2023 - Elsevier
Background Post-operative radiosurgery (SRS) of brain metastases patients is typically
planned on a post-recovery MRI, 2–4 weeks after resection. However, the intracranial …

[HTML][HTML] The relationship between tumor volume and timing of post-resection stereotactic radiosurgery to maximize local control: a critical review

M Yuan, E Behrami, S Pannullo, TH Schwartz… - Cureus, 2019 - ncbi.nlm.nih.gov
After maximally safe neurosurgical resection of brain metastases, stereotactic radiosurgery
(SRS) is now recommended as an alternative to whole-brain radiation therapy (WBRT) …

Efficacy of hypofractionated Gamma Knife radiosurgery in treating surgical beds of metastatic brain tumors

Y Samanci, MA Tepebasili, GD Ardor… - Journal of Clinical …, 2024 - Elsevier
Objective Surgery alone for metastatic brain tumors (METs) often results in local recurrence
due to microscopic residual tumor tissue. While stereotactic radiosurgery (SRS) is commonly …