Sodium sulfite (SS) is a biological derivative of the air pollutant sulfur dioxide, and is often
used as a food and pharmaceutical additive. Improper or excessive SS exposure in liver cell …

Obesity is an exceedingly prevalent and frequent health issue in today's society. Fat
deposition is accompanied by low-grade inflammation in fat tissue and throughout the body …

Background Currently, treatment regimens for visceral leishmaniasis (VL) are limited
because of the presence of numerous adverse effects. Nicotinamide, a readily available and …

The paper reviews some of the mechanisms implicated in hepatotoxicity, which is induced
by an excess of lipids. The paper spans a wide variety of topics: from the molecular …

Lysosomal membrane permeabilization (LMP) has emerged as a significant component of
cellular signaling pathway by which autophagy or cell death is regulated under many …

Background Studies demonstrated the associations of cadmium (Cd) with lipid levels and
dyslipidemia risk, but the mechanisms involved need further exploration. Objectives We …

Alcohol consumption induces hepatocyte damage through complex processes involving
oxidative stress and disrupted metabolism. These factors alter proteomic and epigenetic …

The activation of hypoxia-inducible factors (HIF)-1α and 2α in the liver is closely linked to the
progression of fatty liver diseases. Prior studies indicated that disrupting hepatocyte HIF-2α …

Liver-derived ketone bodies play a crucial role in fasting energy homeostasis by fueling the
brain and peripheral tissues. Ketogenesis also acts as a conduit to remove excess acetyl …

Abstract Background Alcoholic Liver Disease (ALD) is a hepatic disorder resulting from
prolonged or excessive alcohol intake. The predominant manifestation of ALD is fatty liver …