Epilepsy is a chronic neurological condition characterized by recurrent seizures that affects
millions of people worldwide. Comprehension of the complex mechanisms underlying …

The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …

Epileptogenesis is a chronic process that can be triggered by genetic or acquired factors,
and that can continue long after epilepsy diagnosis. In 2015, epileptogenesis is not a …

Background Traumatic brain injury (TBI) causes 10–20% of acquired epilepsy, which
typically develops within 2 years post-injury with poorly understood mechanisms. We …

Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Traumatic Brain Injury (TBI) affects a large proportion and extensive array of individuals in
the population. While precise pathological mechanisms are lacking, the growing base of …

Onset of many forms of epilepsy occurs after an initial epileptogenic insult or as a result of an
identified genetic defect. Given that the precipitating insult is known, these epilepsies are, in …

A biomarker is defined as an objectively measured characteristic of a normal or pathologic
biologic process. Identification and proper validation of biomarkers of epileptogenesis (the …

Traumatic brain injury (TBI) affects an estimated 1.7 million people in the United States and
is a contributing factor to one third of all injury related deaths annually. According to the …