Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease where
chronic inflammation and tissue or organ damage is observed. Due to various suspected …

Many patients with systemic immune-inflammatory and neuro-inflammatory disorders,
including depression, rheumatoid arthritis, systemic lupus erythematosus, Sjögren's disease …

Objective Vitamin D has an important immunomodulatory effect, but there are no trials that
directly address the boosting of serum levels of 25‐hydroxyvitamin D (25 [OH] D) in juvenile …

Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disease with a
prevalence of approximately 1 in 1000. Over the last 30 years, advances in treatment such …

Frailty is a new concept in rheumatology that can help identify people more likely to have
less favorable outcomes. Sarcopenia and inflammaging can be regarded as the biological …

The primary purpose of this study was to identify if serum 25-hydroxyvitamin D (25 (OH) D)
concentrations predict muscular weakness after intense exercise. We hypothesized that pre …

Objective Fatigue is reported in up to 90% of patients with SLE. This study was conducted to
identify the determinants associated with fatigue in a large cohort of patients with SLE, as …

Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology,
although its mechanisms involve genetic, epigenetic and environmental risk factors …

The influence of environmental factors on the development of autoimmune disease is being
broadly investigated to better understand the multifactorial nature of autoimmune …

Fatigue is a complex and multifactorial phenomenon which is often neglected by clinicians.
The aim of this review was to analyze the impact, determinants and management of fatigue …