Abstract The SCUBE [Signal peptide-Complement C1r/C1s, Uegf, Bmp1 (CUB)-Epithelial
growth factor domain-containing protein] family consists of three proteins in vertebrates …

The vascular endothelium plays a vital role in regulating normal vascular function.
Endothelial lining maintains the balance of thrombolytic and fibrinolytic microenvironment in …

Background Diabetic kidney disease (DKD) is the leading cause of death in people with type
2 diabetes mellitus (T2DM). The main objective of this study is to find the potential …

Genome-wide association studies of 146 plasma protein levels in 818 individuals revealed
56 genome-wide significant associations (28 novel) with 47 analytes. Loci associated with …

Apolipoprotein H (ApoH) is a multi-functional plasma glycoprotein that has been associated
with negative health outcomes. ApoH levels have high heritability. We undertook a genome …

Inhibition of atherosclerosis progression has long been the subject of intensive
pathophysiologic investigations. The identification of a novel target molecule to redeem the …

The objective of the present study was to detect the association of the Trp316Ser variant
(rs1801690) near the apolipoprotein H (β2-glycoprotein-I) gene and serum lipid levels in the …

Background Venous thrombosis (VT) is a worldwide medical problem. In order to identify
individuals at high risk early, it is necessary to find more genetic risk factors. Nowadays, the …

Aging is a growing problem worldwide, and the prevalence and mortality of arterial and
venous thromboembolism (VTE) are higher in the elderly than in the young population. To …

Purpose Protein kinase C α (PRKCA) is involved in multiple functions and has been
implicated in heart failure risks and treatment outcomes. This study aims to identify …