The population of adults living with congenital heart disease (CHD) has grown rapidly in
recent decades due to major advances in surgical and medical care. Although the benefits …

Background: Despite developments in surgical techniques and medical care, people with a
Fontan circulation still experience long-term complications; non-invasive therapies to …

The Fontan operation has been the final palliation for patients born with congenital heart
defects with a functional single ventricle for more than 4 decades. The “normal” Fontan …

In patients with congenital heart disease (CHD), reduced exercise capacity can be a
predictor for late complications and may be used to guide interventions. Yet, the …

Background: People with a Fontan circulation usually have moderately impaired exercise
performance, although a subset have high physical performance (“Super-Fontan”), which …

Stress cardiac imaging is the current first line investigation for coronary artery disease
diagnosis and decision making and an adjunctive tool in a range of non-ischaemic …

The Fontan circulation provides definite palliation for children born with a single anatomical
or functional ventricle by diverting systemic venous blood directly to the pulmonary arteries …

Background Despite the frequent use of the 6-minute walk test (6MWT), exercise capacity
has not been assessed with the incremental shuttle walk test (ISWT) in patients who have …

Children born with univentricular hearts undergo staged surgical procedures to a Fontan
circulation. Long‐term experience with Fontan palliation has shown dramatically improved …

The heart of the African clawed frog has a double-inlet and single-outlet ventricle supporting
systemic and pulmonary circulations via a truncus, and a lifespan of 25–30 years. We sought …