Natural products as a source of Alzheimer's drug leads

P Williams, A Sorribas, MJR Howes - Natural product reports, 2011 - pubs.rsc.org
Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …

Clinical features and multidisciplinary approaches to dementia care

JHG Grand, S Caspar… - Journal of multidisciplinary …, 2011 - Taylor & Francis
Dementia is a clinical syndrome of widespread progressive deterioration of cognitive
abilities and normal daily functioning. These cognitive and behavioral impairments pose …

[图书][B] The Maudsley prescribing guidelines

D Taylor, C Paton - 2009 - taylorfrancis.com
One of the most widely used guides to prescribing psychiatric medications, the Tenth Edition
of Maudsley Prescribing Guidelines returns with fully updated content and new sections on …

The potential role of dopamine D3 receptor neurotransmission in cognition

S Nakajima, P Gerretsen, H Takeuchi… - European …, 2013 - Elsevier
Currently available treatments have limited pro-cognitive effects for neuropsychiatric
disorders, such as schizophrenia, Parkinson's disease and Alzheimer's disease. The …

The role of phytochemicals in the treatment and prevention of dementia

MJR Howes, E Perry - Drugs & aging, 2011 - Springer
Dementia pathologies such as Alzheimer's disease (AD) are reaching epidemic proportions,
yet they are not successfully managed by effective symptomatic treatments. Only five drugs …

Pharmacological treatments for neuropsychiatric symptoms of dementia in long-term care: a systematic review

DP Seitz, SS Gill, N Herrmann, S Brisbin… - International …, 2013 - cambridge.org
Background: Medications are frequently prescribed for neuropsychiatric symptoms (NPS)
associated with dementia, although information on the efficacy and safety of medications for …

[HTML][HTML] Non-pharmacologic interventions for persons with dementia

M Berg-Weger, DB Stewart - Missouri medicine, 2017 - ncbi.nlm.nih.gov
Abstract Affecting over 100,000 older Missourians, cognitive impairment is of concern for all
health care providers. With no available pharmacologic treatments to eradicate/diminish …

Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity

JE Marlo, CM Niswender, EL Days, TM Bridges… - Molecular …, 2009 - ASPET
Activators of M1 muscarinic acetylcholine receptors (mAChRs) may provide novel treatments
for schizophrenia and Alzheimer's disease. Unfortunately, the development of M1-active …

Racial and ethnic differences in initiation and discontinuation of antidementia drugs by Medicare beneficiaries

CT Thorpe, NR Fowler, K Harrigan… - Journal of the …, 2016 - Wiley Online Library
Objectives To examine racial and ethnic differences in initiation and time to discontinuation
of antidementia medication in Medicare beneficiaries. Design Retrospective cohort study …

Quality of life in dementia patients in Athens, Greece: predictive factors and the role of caregiver-related factors

AA Mougias, A Politis, CG Lyketsos… - International …, 2011 - cambridge.org
Background: Quality of life (QOL) is increasingly recognized as the main target of currently
available dementia care. Its assessment has grown exponentially in the dementia field, but …