Synthesis, structural, molecular docking, DFT, vibrational spectroscopy, HOMO-LUMO, MEP exploration, antibacterial and antifungal activity of new Fe (III), Co (II) and …
A Abdou - Journal of Molecular Structure, 2022 - Elsevier
Abstract Three new FeLphen, CoLphen and NiLphen hetero-ligand were synthesized,
characterized and theoretically investigated. The new complexes were based on …
characterized and theoretically investigated. The new complexes were based on …
Chemical Composition, Anti-Quorum Sensing, Enzyme Inhibitory, and Antioxidant Properties of Phenolic Extracts of Clinopodium nepeta L. Kuntze
Phenolic extracts of Clinopodium nepeta were prepared and their preliminary phenolic
profiles determined using HPLC-DAD with 26 phenolic standards. Apigenin (21.75±0.41 …
profiles determined using HPLC-DAD with 26 phenolic standards. Apigenin (21.75±0.41 …
New phosphinic and phosphonic acids: Synthesis, antidiabetic, anti-Alzheimer, antioxidant activity, DFT study and SARS-CoV-2 inhibition
Two new α-aminophosphinic (A) and α-aminophosphonic (B) acids were synthesized
through a one-pot three-component reaction with good yields of 89% and 85%, respectively …
through a one-pot three-component reaction with good yields of 89% and 85%, respectively …
New thiophene-derived α-aminophosphonic acids: Synthesis under microwave irradiations, antioxidant and antifungal activities, DFT investigations and SARS-CoV-2 …
Four new α-aminophosphonic acids containing thiophene ring have been synthesized using
simple, neat and catalyst-free conditions, more convenient and eco-friendly method under …
simple, neat and catalyst-free conditions, more convenient and eco-friendly method under …
Design, synthesis, anti-acetylcholinesterase evaluation and molecular modelling studies of novel coumarin-chalcone hybrids
The major enzyme responsible for the hydrolytic breakdown of the neurotransmitter
acetylcholine (ACh) is acetylcholinesterase (AChE). Acetylcholinesterase inhibitors …
acetylcholine (ACh) is acetylcholinesterase (AChE). Acetylcholinesterase inhibitors …
Synthesis, characterization, DFT study and antioxidant activity of (2-hydroxynaphthalen-1-yl) methyl 2-hydroxyphenyl amino phosphonic acid
New molecule α-aminophosphonate namely (2-hydroxynaphthalen-1-yl) methyl 2-
hydroxyphenyl amino phosphonic acid (HMHP) was synthesized by condensation based on …
hydroxyphenyl amino phosphonic acid (HMHP) was synthesized by condensation based on …
New aromatic hydrazones: Synthesis, structural analysis, DFT study, biological activity, ADME-T properties and in silico evaluation of their inhibition of SAS-CoV-2 …
L Adjissi, N Chafai, K Benbouguerra, I Kirouani… - Journal of Molecular …, 2023 - Elsevier
Three new hydrazones namely:(2E)-1-(4-methylphenyl-2-[(thiophen-2-yl) methylidene]
hydrazine (HZ-1),(2E)-1-(4-methylphenyl)-2-[(thiophen-3yl) methylidene] hydrazine (HZ-2) …
hydrazine (HZ-1),(2E)-1-(4-methylphenyl)-2-[(thiophen-3yl) methylidene] hydrazine (HZ-2) …
Antioxidant activity of new synthesized imine and its corresponding α-aminophosphonic acid: Experimental and theoretical evaluation
A Schiff base (I1) and its corresponding α-aminophosphonic acid (P1) were synthesized
using a simple and rapid preparation method and with a chemical yield of up to 75% and …
using a simple and rapid preparation method and with a chemical yield of up to 75% and …
Piperazine selenium nanoparticle (Pipe@ SeNP's): A futuristic anticancer contender against MDA-MB-231 cancer cell line
HSN Prasad, AP Ananda, S Sumathi, K Swathi… - Journal of Molecular …, 2022 - Elsevier
Drug resistance is a major drawback of breast cancer management mainly in treatment
failure. The main objective of the current study is to investigate whether Piperazine selenium …
failure. The main objective of the current study is to investigate whether Piperazine selenium …
Synthesis, characterization, DFT, antioxidant, antibacterial, pharmacokinetics and inhibition of SARS-CoV-2 main protease of some heterocyclic hydrazones
L Adjissi, N Chafai, K Benbouguerra, I Kirouani… - Journal of Molecular …, 2022 - Elsevier
Three hydrazone derivatives have been synthesized using condensation reaction of 4-
hydrazinylbenzoic acid with three aromatic aldehydes namely: thiophene-2-carbaldehyde …
hydrazinylbenzoic acid with three aromatic aldehydes namely: thiophene-2-carbaldehyde …