Progress and challenges in screening for early detection of ovarian cancer

IJ Jacobs, U Menon - Molecular & Cellular Proteomics, 2004 - ASBMB
Ovarian cancer is characterize by few early symptoms, presentation at an advanced stage,
and poor survival. As a result, it is the most frequent cause of death from gynecological …

New tumor markers: CA125 and beyond

RC Bast, D Badgwell, Z Lu, R Marquez… - International Journal of …, 2005 - ijgc.bmj.com
A variety of biomarkers have been developed to monitor growth of ovarian cancer and to
detect disease at an early interval. CA125 (MUC16) has provided a useful serum tumor …

ONCOMINE: a cancer microarray database and integrated data-mining platform

DR Rhodes, J Yu, K Shanker, N Deshpande… - Neoplasia, 2004 - Elsevier
DNA microarray technology has led to an explosion of oncogenomic analyses, generating a
wealth of data and uncovering the complex gene expression patterns of cancer …

National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian …

CM Sturgeon, MJ Duffy, UH Stenman, H Lilja… - 2008 - academic.oup.com
Abstract Background: Updated National Academy of Clinical Biochemistry (NACB)
Laboratory Medicine Practice Guidelines for the use of tumor markers in the clinic have been …

Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer

Z Zhang, RC Bast Jr, Y Yu, J Li, LJ Sokoll, AJ Rai… - Cancer research, 2004 - AACR
Early detection remains the most promising approach to improve long-term survival of
patients with ovarian cancer. In a five-center case-control study, serum proteomic …

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

JB Welsh, LM Sapinoso, SG Kern… - Proceedings of the …, 2003 - National Acad Sciences
Genetic alterations in tumor cells often lead to the emergence of growth-stimulatory
autocrine and paracrine signals, involving overexpression of secreted peptide growth …

Multi-biomarker panel signature as the key to diagnosis of ovarian cancer

T Muinao, HPD Boruah, M Pal - Heliyon, 2019 - cell.com
Early detection of ovarian cancer has been a challenge to manage the high mortality rate
caused by this deadly disease. The trends in mortality have been reduced by the scientific …

Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis

KH Lu, AP Patterson, L Wang, RT Marquez… - Clinical cancer …, 2004 - AACR
Purpose: Advanced-stage epithelial ovarian cancer has a poor prognosis with long-term
survival in less than 30% of patients. When the disease is detected in stage I, more than …

Ovarian cancer biomarkers: moving forward in early detection

VDB Bonifácio - Tumor Microenvironment: The Main Driver of Metabolic …, 2020 - Springer
Ovarian cancer is a silent cancer which rate survival mainly relays in early stage detection.
The discovery of reliable ovarian cancer biomarkers plays a crucial role in the disease …

New predictive biomarkers for ovarian cancer

GA Atallah, NH Abd. Aziz, CK Teik, MN Shafiee… - Diagnostics, 2021 - mdpi.com
Ovarian cancer is the eighth-most common cause of death among women worldwide. In the
absence of distinctive symptoms in the early stages, the majority of women are diagnosed in …