[HTML][HTML] Palmitic acid: physiological role, metabolism and nutritional implications

G Carta, E Murru, S Banni, C Manca - Frontiers in physiology, 2017 - frontiersin.org
Palmitic acid (PA) has been for long time negatively depicted for its putative detrimental
health effects, shadowing its multiple crucial physiological activities. PA is the most common …

[HTML][HTML] Structure-function relationships in pulmonary surfactant membranes: from biophysics to therapy

E Lopez-Rodriguez, J Pérez-Gil - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Pulmonary surfactant is an essential lipid–protein complex to maintain an operative
respiratory surface at the mammalian lungs. It reduces surface tension at the alveolar air …

Pulmonary surfactant: A mighty thin film

F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

[HTML][HTML] Current perspectives in pulmonary surfactant—inhibition, enhancement and evaluation

YY Zuo, RAW Veldhuizen, AW Neumann… - … et Biophysica Acta (BBA …, 2008 - Elsevier
Pulmonary surfactant (PS) is a complicated mixture of approximately 90% lipids and 10%
proteins. It plays an important role in maintaining normal respiratory mechanics by reducing …

[HTML][HTML] Structure of pulmonary surfactant membranes and films: the role of proteins and lipid–protein interactions

J Pérez-Gil - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2008 - Elsevier
The pulmonary surfactant system constitutes an excellent example of how dynamic
membrane polymorphism governs some biological functions through specific lipid–lipid …

[HTML][HTML] Journey to the centre of the lung. The perspective of a mineralogist on the carcinogenic effects of mineral fibres in the lungs

AF Gualtieri - Journal of Hazardous Materials, 2023 - Elsevier
This work reviews the bio-chemical mechanisms leading to adverse effects produced when
mineral fibres are inhaled and transported in the lungs from the perspective of a …

Lung surfactant: Function and composition in the context of development and respiratory physiology

W Bernhard - Annals of Anatomy-Anatomischer Anzeiger, 2016 - Elsevier
Lung surfactant is a complex with a unique phospholipid and protein composition. Its
specific function is to reduce surface tension at the pulmonary air–liquid interface. The …

Simulated biological fluids–a systematic review of their biological relevance and use in relation to inhalation toxicology of particles and fibres

E Innes, HHP Yiu, P McLean, W Brown… - Critical Reviews in …, 2021 - Taylor & Francis
The use of simulated biological fluids (SBFs) is a promising in vitro technique to better
understand the release mechanisms and possible in vivo behaviour of materials, including …

Understanding the principle biophysics concepts of pulmonary surfactant in health and disease

C Autilio, J Pérez-Gil - Archives of Disease in Childhood-Fetal and …, 2019 - fn.bmj.com
Pulmonary surfactant (PS) is a lipid-protein complex essential to stabilise the delicate
structure of mammalian alveoli along with successive compression-expansion respiratory …

[HTML][HTML] Mouse lipidomics reveals inherent flexibility of a mammalian lipidome

MA Surma, MJ Gerl, R Herzog, J Helppi, K Simons… - Scientific reports, 2021 - nature.com
Lipidomics has become an indispensable method for the quantitative assessment of lipid
metabolism in basic, clinical, and pharmaceutical research. It allows for the generation of …